Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | txpA-MW1433/- |
Location | 2045113..2045420 | Replicon | chromosome |
Accession | NZ_CP019574 | ||
Organism | Staphylococcus aureus strain USA400-0051 |
Toxin (Protein)
Gene name | txpA | Uniprot ID | Q2FWU9 |
Locus tag | SAU400_RS10565 | Protein ID | WP_011447039.1 |
Coordinates | 2045244..2045420 (-) | Length | 59 a.a. |
Antitoxin (RNA)
Gene name | MW1433 | ||
Locus tag | - | ||
Coordinates | 2045113..2045252 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
SAU400_RS10505 | 2040679..2040858 | + | 180 | WP_000669791.1 | hypothetical protein | - |
SAU400_RS10515 | 2041169..2041429 | + | 261 | WP_001791826.1 | hypothetical protein | - |
SAU400_RS10520 | 2041482..2041832 | - | 351 | WP_000702263.1 | complement inhibitor SCIN-A | - |
SAU400_RS10525 | 2042343..2042678 | - | 336 | Protein_1933 | SH3 domain-containing protein | - |
SAU400_RS10545 | 2043329..2043820 | - | 492 | WP_000920039.1 | staphylokinase | - |
SAU400_RS10550 | 2044011..2044766 | - | 756 | WP_000861038.1 | CHAP domain-containing protein | - |
SAU400_RS10555 | 2044778..2045032 | - | 255 | WP_000611512.1 | phage holin | - |
SAU400_RS10560 | 2045084..2045191 | + | 108 | WP_031762631.1 | hypothetical protein | - |
- | 2045113..2045252 | + | 140 | NuclAT_0 | - | Antitoxin |
- | 2045113..2045252 | + | 140 | NuclAT_0 | - | Antitoxin |
- | 2045113..2045252 | + | 140 | NuclAT_0 | - | Antitoxin |
- | 2045113..2045252 | + | 140 | NuclAT_0 | - | Antitoxin |
SAU400_RS10565 | 2045244..2045420 | - | 177 | WP_011447039.1 | putative holin-like toxin | Toxin |
SAU400_RS10570 | 2045528..2046301 | - | 774 | WP_000750412.1 | staphylococcal enterotoxin type A | - |
SAU400_RS10575 | 2046674..2047048 | - | 375 | WP_000340977.1 | hypothetical protein | - |
SAU400_RS10580 | 2047104..2047391 | - | 288 | WP_001262624.1 | hypothetical protein | - |
SAU400_RS10585 | 2047437..2047589 | - | 153 | WP_001000058.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
inside | Prophage | - | scn / sak / sea / selq / selk / hlb / groEL | 2041482..2096979 | 55497 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 59 a.a. Molecular weight: 6849.45 Da Isoelectric Point: 10.6777
>T72691 WP_011447039.1 NZ_CP019574:c2045420-2045244 [Staphylococcus aureus]
MDRWWLSEYKEVVPMVALLKSLERRRLMITISTMLQFGLFLIALIGLVIKLIELSNKK
MDRWWLSEYKEVVPMVALLKSLERRRLMITISTMLQFGLFLIALIGLVIKLIELSNKK
Download Length: 177 bp
>T72691 NZ_CP019574:c2045420-2045244 [Staphylococcus aureus]
TTGGATAGATGGTGGCTATCTGAGTATAAGGAGGTGGTGCCTATGGTGGCATTACTGAAATCTTTAGAAAGGAGACGCCT
AATGATTACAATTAGTACCATGTTGCAGTTTGGTTTATTCCTTATTGCATTGATAGGTCTAGTAATCAAGCTTATTGAAT
TAAGCAATAAAAAATAA
TTGGATAGATGGTGGCTATCTGAGTATAAGGAGGTGGTGCCTATGGTGGCATTACTGAAATCTTTAGAAAGGAGACGCCT
AATGATTACAATTAGTACCATGTTGCAGTTTGGTTTATTCCTTATTGCATTGATAGGTCTAGTAATCAAGCTTATTGAAT
TAAGCAATAAAAAATAA
Antitoxin
Download Length: 140 bp
>AT72691 NZ_CP019574:2045113-2045252 [Staphylococcus aureus]
ATATATAGAAAAAGGGCAACATGCGCAAACATGTTACCCTAGTGAGCCCGTTAAAAAGACGGTGGCTATTTTAGATTAAA
GATTAAATTAATAACCATTTAACCATCGAAACCAGCCAAAGTTAGCGATGGTTATTTTTT
ATATATAGAAAAAGGGCAACATGCGCAAACATGTTACCCTAGTGAGCCCGTTAAAAAGACGGTGGCTATTTTAGATTAAA
GATTAAATTAATAACCATTTAACCATCGAAACCAGCCAAAGTTAGCGATGGTTATTTTTT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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