Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) CD-RCd/-
Location 3337426..3337641 Replicon chromosome
Accession NZ_CP016318
Organism Clostridioides difficile strain 630 delta erm

Toxin (Protein)


Gene name CD2889 Uniprot ID Q183X5
Locus tag CDIF630erm_RS20760 Protein ID WP_011861731.1
Coordinates 3337498..3337641 (-) Length 48 a.a.

Antitoxin (RNA)


Gene name RCd8
Locus tag -
Coordinates 3337426..3337572 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 48 a.a.        Molecular weight: 5399.34 Da        Isoelectric Point: 10.8277

>T64415 WP_011861731.1 NZ_CP016318:c3337641-3337498 [Clostridioides difficile]
MSEFLLGVLASLTASFITYIISRKVKSHSGRSDFELDVKIKFNKKRH

Download         Length: 144 bp

>T64415 NZ_CP016318:c3337641-3337498 [Clostridioides difficile]
ATGAGCGAATTTTTACTAGGAGTGTTAGCTAGTTTAACAGCTAGCTTTATTACATATATTATTTCCAGAAAAGTAAAAAG
CCACTCTGGCAGGAGTGACTTTGAGCTTGATGTAAAAATCAAGTTTAATAAAAAACGACATTAA

Antitoxin


Download         Length: 147 bp

>AT64415 NZ_CP016318:3337426-3337572 [Clostridioides difficile]
GTAAATTCGTATCAAAAACAAAAAAAGAAACTACAATCTATTAGCCTAGAGTGAAGTTTCATTAACTAAATATTAATGTC
GTTTTTTATTAAACTTGATTTTTACATCAAGCTCAAAGTCACTCCTGCCAGAGTGGCTTTTTACTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A069A3R1

Antitoxin

Download structure file

References