Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | CD-RCd/- |
Location | 1474347..1474543 | Replicon | chromosome |
Accession | NZ_CP016106 | ||
Organism | Clostridioides difficile strain DSM 29637 |
Toxin (Protein)
Gene name | CD1418.2 | Uniprot ID | Q18BT8 |
Locus tag | CDIF29637_RS07100 | Protein ID | WP_009902496.1 |
Coordinates | 1474347..1474499 (+) | Length | 51 a.a. |
Antitoxin (RNA)
Gene name | CD630_n00500 | ||
Locus tag | - | ||
Coordinates | 1474443..1474543 (-) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
CDIF29637_RS07070 | 1469924..1470517 | - | 594 | WP_003438546.1 | DUF308 domain-containing protein | - |
CDIF29637_RS07075 | 1470624..1471052 | + | 429 | WP_021369464.1 | DMT family transporter | - |
CDIF29637_RS07080 | 1471119..1471787 | + | 669 | WP_003429358.1 | diphthine--ammonia ligase | - |
CDIF29637_RS07085 | 1471905..1473260 | - | 1356 | WP_021369460.1 | MATE family efflux transporter | - |
CDIF29637_RS07100 | 1474347..1474499 | + | 153 | WP_009902496.1 | hypothetical protein | Toxin |
- | 1474443..1474543 | - | 101 | NuclAT_5 | - | Antitoxin |
CDIF29637_RS07105 | 1475657..1477390 | - | 1734 | WP_009902497.1 | diguanylate cyclase | - |
CDIF29637_RS07110 | 1477630..1478475 | - | 846 | WP_009889222.1 | GGDEF domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 51 a.a. Molecular weight: 5742.81 Da Isoelectric Point: 10.9178
>T64232 WP_009902496.1 NZ_CP016106:1474347-1474499 [Clostridioides difficile]
MDNFLQGVLASLVASLIVYLNSKLFKKVKSHSGRSDFSFELKIKFKKNKH
MDNFLQGVLASLVASLIVYLNSKLFKKVKSHSGRSDFSFELKIKFKKNKH
Download Length: 153 bp
>T64232 NZ_CP016106:1474347-1474499 [Clostridioides difficile]
ATGGATAATTTTTTACAAGGTGTACTAGCAAGTTTAGTTGCCAGTTTAATAGTTTACTTAAATAGTAAATTGTTTAAAAA
AGTAAAAAGCCACTCTGGCAGGAGTGACTTTAGTTTTGAACTAAAAATCAAGTTCAAAAAGAATAAACATTAG
ATGGATAATTTTTTACAAGGTGTACTAGCAAGTTTAGTTGCCAGTTTAATAGTTTACTTAAATAGTAAATTGTTTAAAAA
AGTAAAAAGCCACTCTGGCAGGAGTGACTTTAGTTTTGAACTAAAAATCAAGTTCAAAAAGAATAAACATTAG
Antitoxin
Download Length: 101 bp
>AT64232 NZ_CP016106:c1474543-1474443 [Clostridioides difficile]
AAGAAGAACTACAATCTATTTAGACGTAGAGTGAAGTTCAAATACTAATGTTTATTCTTTTTGAACTTGATTTTTAGTTC
AAAACTAAAGTCACTCCTGCC
AAGAAGAACTACAATCTATTTAGACGTAGAGTGAAGTTCAAATACTAATGTTTATTCTTTTTGAACTTGATTTTTAGTTC
AAAACTAAAGTCACTCCTGCC
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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