Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) CD-RCd/-
Location 1474347..1474543 Replicon chromosome
Accession NZ_CP016106
Organism Clostridioides difficile strain DSM 29637

Toxin (Protein)


Gene name CD1418.2 Uniprot ID Q18BT8
Locus tag CDIF29637_RS07100 Protein ID WP_009902496.1
Coordinates 1474347..1474499 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name CD630_n00500
Locus tag -
Coordinates 1474443..1474543 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CDIF29637_RS07070 1469924..1470517 - 594 WP_003438546.1 DUF308 domain-containing protein -
CDIF29637_RS07075 1470624..1471052 + 429 WP_021369464.1 DMT family transporter -
CDIF29637_RS07080 1471119..1471787 + 669 WP_003429358.1 diphthine--ammonia ligase -
CDIF29637_RS07085 1471905..1473260 - 1356 WP_021369460.1 MATE family efflux transporter -
CDIF29637_RS07100 1474347..1474499 + 153 WP_009902496.1 hypothetical protein Toxin
- 1474443..1474543 - 101 NuclAT_5 - Antitoxin
CDIF29637_RS07105 1475657..1477390 - 1734 WP_009902497.1 diguanylate cyclase -
CDIF29637_RS07110 1477630..1478475 - 846 WP_009889222.1 GGDEF domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5742.81 Da        Isoelectric Point: 10.9178

>T64232 WP_009902496.1 NZ_CP016106:1474347-1474499 [Clostridioides difficile]
MDNFLQGVLASLVASLIVYLNSKLFKKVKSHSGRSDFSFELKIKFKKNKH

Download         Length: 153 bp

>T64232 NZ_CP016106:1474347-1474499 [Clostridioides difficile]
ATGGATAATTTTTTACAAGGTGTACTAGCAAGTTTAGTTGCCAGTTTAATAGTTTACTTAAATAGTAAATTGTTTAAAAA
AGTAAAAAGCCACTCTGGCAGGAGTGACTTTAGTTTTGAACTAAAAATCAAGTTCAAAAAGAATAAACATTAG

Antitoxin


Download         Length: 101 bp

>AT64232 NZ_CP016106:c1474543-1474443 [Clostridioides difficile]
AAGAAGAACTACAATCTATTTAGACGTAGAGTGAAGTTCAAATACTAATGTTTATTCTTTTTGAACTTGATTTTTAGTTC
AAAACTAAAGTCACTCCTGCC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A069ACY9

Antitoxin

Download structure file

References