Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1908362..1908544 Replicon chromosome
Accession NZ_CP015447
Organism Staphylococcus aureus strain M92

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag A6V38_RS09635 Protein ID WP_001801861.1
Coordinates 1908362..1908457 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1908485..1908544 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A6V38_RS09585 1904021..1904647 + 627 WP_000669046.1 hypothetical protein -
A6V38_RS09590 1904688..1905032 + 345 WP_000627551.1 DUF3969 family protein -
A6V38_RS09595 1905130..1905681 + 552 WP_000414205.1 hypothetical protein -
A6V38_RS09600 1905899..1906540 - 642 WP_000494956.1 ImmA/IrrE family metallo-endopeptidase -
A6V38_RS09605 1906654..1906839 - 186 WP_000809857.1 hypothetical protein -
A6V38_RS09610 1906841..1907017 - 177 WP_000375476.1 hypothetical protein -
A6V38_RS09615 1907028..1907411 - 384 WP_000070811.1 hypothetical protein -
A6V38_RS09625 1908015..1908158 - 144 WP_001549059.1 transposase -
A6V38_RS09635 1908362..1908457 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1908485..1908544 - 60 - - Antitoxin
A6V38_RS09640 1908580..1908681 + 102 WP_001791893.1 hypothetical protein -
A6V38_RS09645 1908659..1908835 - 177 Protein_1810 transposase -
A6V38_RS09650 1909029..1909406 - 378 WP_001037045.1 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA 1901461..1940381 38920


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T63078 WP_001801861.1 NZ_CP015447:1908362-1908457 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T63078 NZ_CP015447:1908362-1908457 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 60 bp

>AT63078 NZ_CP015447:c1908544-1908485 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References