Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) fst-RNAII/-
Location 2207429..2207623 Replicon chromosome
Accession NZ_CP014949
Organism Enterococcus faecalis strain LD33

Toxin (Protein)


Gene name fst Uniprot ID -
Locus tag A3777_RS14665 Protein ID WP_142954371.1
Coordinates 2207528..2207623 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name RNAII
Locus tag -
Coordinates 2207429..2207493 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A3777_RS10920 2203053..2204801 + 1749 WP_002403688.1 PTS transporter subunit EIIC -
A3777_RS10925 2204792..2206825 + 2034 WP_002355275.1 transcription antiterminator -
A3777_RS10930 2206836..2207270 + 435 WP_002355276.1 PTS sugar transporter subunit IIA -
- 2207429..2207493 + 65 - - Antitoxin
A3777_RS14665 2207528..2207623 - 96 WP_142954371.1 type I toxin-antitoxin system Fst family toxin Toxin
A3777_RS10940 2207869..2209641 + 1773 WP_002387897.1 PTS mannitol transporter subunit IICBA -
A3777_RS10945 2209656..2210093 + 438 WP_002355279.1 PTS sugar transporter subunit IIA -
A3777_RS10950 2210108..2211262 + 1155 WP_002355280.1 mannitol-1-phosphate 5-dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
flank IS/Tn - - 2211391..2212194 803


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3645.44 Da        Isoelectric Point: 4.6275

>T61943 WP_142954371.1 NZ_CP014949:c2207623-2207528 [Enterococcus faecalis]
MYEIVTKVLVPIFVGIVLKLVTIWLEKQNEE

Download         Length: 96 bp

>T61943 NZ_CP014949:c2207623-2207528 [Enterococcus faecalis]
ATGTACGAGATTGTCACAAAAGTTCTTGTGCCGATTTTTGTCGGGATTGTCCTGAAACTTGTAACCATTTGGTTGGAAAA
ACAGAACGAGGAATAA

Antitoxin


Download         Length: 65 bp

>AT61943 NZ_CP014949:2207429-2207493 [Enterococcus faecalis]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATTGCGGTAGGGTGTCTTTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References