Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | sprA1-sprA1AS/- |
Location | 1972220..1972402 | Replicon | chromosome |
Accession | NZ_CP014438 | ||
Organism | Staphylococcus aureus strain USA300-SUR22 |
Toxin (Protein)
Gene name | sprA1 | Uniprot ID | - |
Locus tag | AYM35_RS15725 | Protein ID | WP_001801861.1 |
Coordinates | 1972220..1972315 (+) | Length | 32 a.a. |
Antitoxin (RNA)
Gene name | sprA1AS | ||
Locus tag | - | ||
Coordinates | 1972343..1972402 (-) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
AYM35_RS10130 | 1967880..1968506 | + | 627 | Protein_1903 | hypothetical protein | - |
AYM35_RS10135 | 1968547..1968891 | + | 345 | WP_000627551.1 | DUF3969 family protein | - |
AYM35_RS10140 | 1968989..1969540 | + | 552 | WP_000414205.1 | hypothetical protein | - |
AYM35_RS10145 | 1969758..1970399 | - | 642 | WP_000494956.1 | ImmA/IrrE family metallo-endopeptidase | - |
AYM35_RS10150 | 1970513..1970698 | - | 186 | WP_000809857.1 | hypothetical protein | - |
AYM35_RS10155 | 1970700..1970876 | - | 177 | WP_000375476.1 | hypothetical protein | - |
AYM35_RS10160 | 1970887..1971270 | - | 384 | WP_000070811.1 | hypothetical protein | - |
AYM35_RS10170 | 1971874..1972017 | - | 144 | WP_001549059.1 | transposase | - |
AYM35_RS15725 | 1972220..1972315 | + | 96 | WP_001801861.1 | type I toxin-antitoxin system Fst family toxin PepA1 | Toxin |
- | 1972343..1972402 | - | 60 | - | - | Antitoxin |
AYM35_RS10175 | 1972438..1972539 | + | 102 | WP_001791893.1 | hypothetical protein | - |
AYM35_RS10180 | 1972517..1972693 | - | 177 | Protein_1913 | transposase | - |
AYM35_RS10185 | 1972887..1973264 | - | 378 | WP_001037045.1 | DUF1433 domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
inside | Prophage | - | lukD / hlgA | 1965320..2005491 | 40171 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 32 a.a. Molecular weight: 3554.32 Da Isoelectric Point: 10.4449
>T61178 WP_001801861.1 NZ_CP014438:1972220-1972315 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK
Download Length: 96 bp
>T61178 NZ_CP014438:1972220-1972315 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG
Antitoxin
Download Length: 60 bp
>AT61178 NZ_CP014438:c1972402-1972343 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|