Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-MazE
Location 474055..474534 Replicon chromosome
Accession NZ_CP012832
Organism Synechocystis sp. PCC 6803 substr. GT-G

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag AOY38_RS02250 Protein ID WP_010871640.1
Coordinates 474055..474306 (-) Length 84 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag AOY38_RS02255 Protein ID WP_010871641.1
Coordinates 474307..474534 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AOY38_RS02230 469103..469648 - 546 WP_010871636.1 alpha/beta hydrolase -
AOY38_RS02235 469694..471016 + 1323 WP_010871637.1 hypothetical protein -
AOY38_RS02240 471182..473032 + 1851 WP_010871638.1 ATP-dependent zinc metalloprotease FtsH3 -
AOY38_RS16995 473190..473777 + 588 Protein_444 IS5 family transposase -
AOY38_RS02250 474055..474306 - 252 WP_010871640.1 type II toxin-antitoxin system VapC family toxin Toxin
AOY38_RS02255 474307..474534 - 228 WP_010871641.1 virulence factor Antitoxin
AOY38_RS02260 474613..474894 - 282 WP_020861443.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family -
AOY38_RS02265 474891..475109 - 219 WP_010871642.1 hypothetical protein -
AOY38_RS02270 475212..475547 - 336 WP_010871643.1 DUF86 domain-containing protein -
AOY38_RS02275 475537..475845 - 309 WP_010871644.1 nucleotidyltransferase family protein -
AOY38_RS02280 475975..477501 - 1527 WP_010871645.1 RNA-directed DNA polymerase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
flank IS/Tn - - 473516..473764 248


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-80)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9540.13 Da        Isoelectric Point: 7.9952

>T57266 WP_010871640.1 NZ_CP012832:c474306-474055 [Synechocystis sp. PCC 6803]
MKYLLDTNICIYLIKKKPFKVLAKFQTLEISDIGISSITVAELEYGVSKSQQQSKNRDALMQFLMPLEIVEFNSGSGDRL
WQH

Download         Length: 252 bp

>T57266 NZ_CP012832:c474306-474055 [Synechocystis sp. PCC 6803]
ATGAAGTATTTACTAGATACGAATATTTGCATTTATCTCATTAAGAAGAAACCGTTTAAAGTCTTGGCAAAATTTCAAAC
CCTGGAGATATCAGACATTGGTATTTCATCCATTACCGTGGCGGAATTAGAATATGGTGTCAGTAAAAGTCAACAACAAT
CGAAAAATCGTGATGCCTTAATGCAATTCTTGATGCCGCTAGAAATCGTGGAATTTAATTCAGGAAGCGGCGATCGCCTA
TGGCAACATTAG

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8538.69 Da        Isoelectric Point: 4.2840

>AT57266 WP_010871641.1 NZ_CP012832:c474534-474307 [Synechocystis sp. PCC 6803]
MNTAQISTDGTHQIVILPENFTIAGSEVYIKKIGSTIILIAKNNPWQSLIESLDQFSDDFMKTREQPPLDIREEF

Download         Length: 228 bp

>AT57266 NZ_CP012832:c474534-474307 [Synechocystis sp. PCC 6803]
ATGAACACAGCTCAAATTAGCACCGATGGCACCCATCAAATCGTTATTTTACCAGAAAACTTTACGATAGCCGGAAGCGA
AGTTTACATTAAAAAAATTGGAAGTACAATTATTTTGATTGCTAAAAATAACCCTTGGCAATCCTTAATTGAAAGCTTAG
ATCAATTTTCAGATGATTTTATGAAAACTAGGGAACAGCCTCCCTTAGATATACGAGAAGAGTTCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References