56002

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1347860..1348094 Replicon chromosome
Accession NZ_CP012140
Organism Shigella flexneri 4c strain 1205

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1347990..1348093 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1347860..1348094 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AD871_RS07435 1344415..1345077 - 663 WP_000944268.1 exodeoxyribonuclease X -
AD871_RS07440 1345101..1345757 - 657 Protein_1343 carbon-nitrogen hydrolase family protein -
AD871_RS07445 1345859..1346089 - 231 WP_000916763.1 DNA polymerase III subunit theta -
AD871_RS07450 1346228..1346602 + 375 WP_000168747.1 CopC domain-containing protein YobA -
AD871_RS28620 1346606..1347478 + 873 Protein_1346 copper homeostasis membrane protein CopD -
AD871_RS07465 1347491..1347832 + 342 WP_000976476.1 YebY family protein -
- 1347860..1348094 - 235 - - Antitoxin
- 1347990..1348093 + 104 - - Toxin
AD871_RS30425 1348225..1349302 - 1078 Protein_1348 phage integrase Arm DNA-binding domain-containing protein -
AD871_RS28635 1349268..1349549 - 282 WP_005127484.1 excisionase -
AD871_RS07480 1349666..1350514 - 849 Protein_1350 IS3-like element IS600 family transposase -
AD871_RS28640 1350569..1351764 + 1196 Protein_1351 IS3 family transposase -
AD871_RS07500 1351807..1352117 - 311 Protein_1352 transposase -
AD871_RS07505 1352181..1352648 + 468 Protein_1353 DNA-binding transcriptional regulator PgrR -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 1342358..1358805 16447


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences

Toxin        


Download         Length: 104 bp

>T56002 NZ_CP012140:1347990-1348093 [Shigella flexneri 4c]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT56002 NZ_CP012140:c1348094-1347860 [Shigella flexneri 4c]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures

Antitoxin

Download structure file

Antitoxin

Download structure file

References