Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) CD-RCd/-
Location 1534302..1534498 Replicon chromosome
Accession NZ_CP011847
Organism Clostridioides difficile strain DSM 27639

Toxin (Protein)


Gene name CD1418.2 Uniprot ID Q18BT8
Locus tag CDIF27639_RS07445 Protein ID WP_009902496.1
Coordinates 1534302..1534454 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name CD630_n00500
Locus tag -
Coordinates 1534398..1534498 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CDIF27639_RS07415 1529842..1530435 - 594 WP_003438546.1 DUF308 domain-containing protein -
CDIF27639_RS07420 1530542..1530970 + 429 WP_011861207.1 DMT family transporter -
CDIF27639_RS07425 1531037..1531705 + 669 WP_003429358.1 diphthine--ammonia ligase -
CDIF27639_RS07430 1531823..1533178 - 1356 WP_003438549.1 MATE family efflux transporter -
CDIF27639_RS07445 1534302..1534454 + 153 WP_009902496.1 hypothetical protein Toxin
- 1534398..1534498 - 101 NuclAT_4 - Antitoxin
CDIF27639_RS07450 1535884..1537617 - 1734 WP_009902497.1 diguanylate cyclase -
CDIF27639_RS07455 1537857..1538702 - 846 WP_009889222.1 GGDEF domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5742.81 Da        Isoelectric Point: 10.9178

>T55094 WP_009902496.1 NZ_CP011847:1534302-1534454 [Clostridioides difficile]
MDNFLQGVLASLVASLIVYLNSKLFKKVKSHSGRSDFSFELKIKFKKNKH

Download         Length: 153 bp

>T55094 NZ_CP011847:1534302-1534454 [Clostridioides difficile]
ATGGATAATTTTTTACAAGGTGTACTAGCAAGTTTAGTTGCCAGTTTAATAGTTTACTTAAATAGTAAATTGTTTAAAAA
AGTAAAAAGCCACTCTGGCAGGAGTGACTTTAGTTTTGAACTAAAAATCAAGTTCAAAAAGAATAAACATTAG

Antitoxin


Download         Length: 101 bp

>AT55094 NZ_CP011847:c1534498-1534398 [Clostridioides difficile]
AAGAAGAACTACAATCTATTTAGACGTAGAGTGAAGTTCAAATACTAATGTTTATTCTTTTTGAACTTGATTTTTAGTTC
AAAACTAAAGTCACTCCTGCC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A069ACY9

Antitoxin

Download structure file

References