Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) CD-RCd/-
Location 1629387..1629583 Replicon chromosome
Accession NZ_CP010905
Organism Clostridioides difficile 630

Toxin (Protein)


Gene name CD1418.2 Uniprot ID Q18BT8
Locus tag CDIF630_RS20485 Protein ID WP_009902496.1
Coordinates 1629387..1629539 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name CD630_n00500
Locus tag -
Coordinates 1629483..1629583 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CDIF630_RS07975 1624927..1625520 - 594 WP_003438546.1 DUF308 domain-containing protein -
CDIF630_RS07980 1625627..1626055 + 429 WP_011861207.1 DMT family transporter -
CDIF630_RS07985 1626122..1626790 + 669 WP_003429358.1 diphthine--ammonia ligase -
CDIF630_RS07990 1626908..1628263 - 1356 WP_003438549.1 MATE family efflux transporter -
CDIF630_RS20485 1629387..1629539 + 153 WP_009902496.1 hypothetical protein Toxin
- 1629483..1629583 - 101 NuclAT_15 - Antitoxin
CDIF630_RS08005 1630969..1632702 - 1734 WP_009902497.1 diguanylate cyclase -
CDIF630_RS08010 1632942..1633787 - 846 WP_009889222.1 GGDEF domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5742.81 Da        Isoelectric Point: 10.9178

>T53085 WP_009902496.1 NZ_CP010905:1629387-1629539 [Clostridioides difficile 630]
MDNFLQGVLASLVASLIVYLNSKLFKKVKSHSGRSDFSFELKIKFKKNKH

Download         Length: 153 bp

>T53085 NZ_CP010905:1629387-1629539 [Clostridioides difficile 630]
ATGGATAATTTTTTACAAGGTGTACTAGCAAGTTTAGTTGCCAGTTTAATAGTTTACTTAAATAGTAAATTGTTTAAAAA
AGTAAAAAGCCACTCTGGCAGGAGTGACTTTAGTTTTGAACTAAAAATCAAGTTCAAAAAGAATAAACATTAG

Antitoxin


Download         Length: 101 bp

>AT53085 NZ_CP010905:c1629583-1629483 [Clostridioides difficile 630]
AAGAAGAACTACAATCTATTTAGACGTAGAGTGAAGTTCAAATACTAATGTTTATTCTTTTTGAACTTGATTTTTAGTTC
AAAACTAAAGTCACTCCTGCC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A069ACY9

Antitoxin

Download structure file

References