51917

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1929116..1929298 Replicon chromosome
Accession NZ_CP010300
Organism Staphylococcus aureus strain ATCC BAA1680

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag RM28_RS15405 Protein ID WP_144245636.1
Coordinates 1929116..1929211 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1929239..1929298 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RM28_RS15550 1924362..1924700 + 339 WP_173401752.1 hypothetical protein -
RM28_RS08835 1924776..1925402 + 627 Protein_1841 hypothetical protein -
RM28_RS08840 1925443..1925787 + 345 WP_000627551.1 DUF3969 family protein -
RM28_RS08845 1925885..1926436 + 552 WP_000414205.1 hypothetical protein -
RM28_RS08850 1926654..1927295 - 642 WP_000494956.1 ImmA/IrrE family metallo-endopeptidase -
RM28_RS08855 1927409..1927594 - 186 WP_000809857.1 hypothetical protein -
RM28_RS14540 1927596..1927772 - 177 WP_000375476.1 hypothetical protein -
RM28_RS08865 1927783..1928166 - 384 WP_000070811.1 hypothetical protein -
RM28_RS14550 1928770..1928913 - 144 WP_001549059.1 transposase -
RM28_RS15405 1929116..1929211 + 96 WP_144245636.1 type I toxin-antitoxin system Fst family toxin Toxin
- 1929239..1929298 - 60 - - Antitoxin
RM28_RS14555 1929334..1929435 + 102 WP_001791893.1 hypothetical protein -
RM28_RS14560 1929413..1929589 - 177 Protein_1851 transposase -
RM28_RS08875 1929783..1930160 - 378 WP_001037045.1 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA 1922215..1962387 40172


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T51917 WP_144245636.1 NZ_CP010300:1929116-1929211 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T51917 NZ_CP010300:1929116-1929211 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 60 bp

>AT51917 NZ_CP010300:c1929298-1929239 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References