Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1929115..1929297 Replicon chromosome
Accession NZ_CP010298
Organism Staphylococcus aureus strain ATCC BAA1680

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag RM31_RS15405 Protein ID WP_001801861.1
Coordinates 1929115..1929210 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1929238..1929297 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RM31_RS15545 1924361..1924699 + 339 WP_173401752.1 hypothetical protein -
RM31_RS08840 1924775..1925401 + 627 Protein_1842 hypothetical protein -
RM31_RS08845 1925442..1925786 + 345 WP_000627551.1 DUF3969 family protein -
RM31_RS08850 1925884..1926435 + 552 WP_000414205.1 hypothetical protein -
RM31_RS08855 1926653..1927294 - 642 WP_000494956.1 ImmA/IrrE family metallo-endopeptidase -
RM31_RS08860 1927408..1927593 - 186 WP_000809857.1 hypothetical protein -
RM31_RS14555 1927595..1927771 - 177 WP_000375476.1 hypothetical protein -
RM31_RS08870 1927782..1928165 - 384 WP_000070811.1 hypothetical protein -
RM31_RS14565 1928769..1928912 - 144 WP_001549059.1 transposase -
RM31_RS15405 1929115..1929210 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1929238..1929297 - 60 - - Antitoxin
RM31_RS14570 1929333..1929434 + 102 WP_001791893.1 hypothetical protein -
RM31_RS14575 1929412..1929588 - 177 Protein_1852 transposase -
RM31_RS08880 1929782..1930159 - 378 WP_001037045.1 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA 1922214..1962386 40172


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T51885 WP_001801861.1 NZ_CP010298:1929115-1929210 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T51885 NZ_CP010298:1929115-1929210 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 60 bp

>AT51885 NZ_CP010298:c1929297-1929238 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References