Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | mazEF/PemK-MazE |
Location | 1778742..1779283 | Replicon | chromosome |
Accession | NZ_CP009790 | ||
Organism | Xylella fastidiosa strain U24d |
Toxin (Protein)
Gene name | mazF | Uniprot ID | - |
Locus tag | XFUD_RS08585 | Protein ID | WP_031336866.1 |
Coordinates | 1778742..1779065 (-) | Length | 108 a.a. |
Antitoxin (Protein)
Gene name | mazE | Uniprot ID | Q9PCB8 |
Locus tag | XFUD_RS08590 | Protein ID | WP_010894329.1 |
Coordinates | 1779062..1779283 (-) | Length | 74 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
XFUD_RS08560 | 1775686..1776378 | + | 693 | WP_031336589.1 | 7-cyano-7-deazaguanine synthase QueC | - |
XFUD_RS08570 | 1776513..1776884 | - | 372 | Protein_1555 | hypothetical protein | - |
XFUD_RS08575 | 1776988..1778166 | + | 1179 | WP_010894325.1 | replication initiation factor domain-containing protein | - |
XFUD_RS08580 | 1778153..1778485 | + | 333 | WP_010894326.1 | hypothetical protein | - |
XFUD_RS13485 | 1778498..1778653 | + | 156 | WP_155114993.1 | hypothetical protein | - |
XFUD_RS08585 | 1778742..1779065 | - | 324 | WP_031336866.1 | type II toxin-antitoxin system PemK/MazF family toxin | Toxin |
XFUD_RS08590 | 1779062..1779283 | - | 222 | WP_010894329.1 | antitoxin MazE family protein | Antitoxin |
XFUD_RS08595 | 1779569..1780003 | - | 435 | WP_010894330.1 | DUF3693 domain-containing protein | - |
XFUD_RS08600 | 1780144..1780446 | + | 303 | WP_010894331.1 | hypothetical protein | - |
XFUD_RS13490 | 1780433..1780747 | + | 315 | WP_143704178.1 | hypothetical protein | - |
XFUD_RS08605 | 1780751..1780933 | + | 183 | WP_023906503.1 | hypothetical protein | - |
XFUD_RS13495 | 1781062..1781241 | - | 180 | WP_023907626.1 | hypothetical protein | - |
XFUD_RS08615 | 1781501..1781929 | + | 429 | Protein_1566 | hypothetical protein | - |
XFUD_RS08620 | 1781933..1782600 | + | 668 | Protein_1567 | hypothetical protein | - |
XFUD_RS08625 | 1782593..1782877 | + | 285 | WP_010894335.1 | DUF2523 domain-containing protein | - |
XFUD_RS08630 | 1782877..1783947 | + | 1071 | WP_010894336.1 | zonular occludens toxin domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
inside | Prophage | - | - | 1775287..1791435 | 16148 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 108 a.a. Molecular weight: 11771.81 Da Isoelectric Point: 7.9848
>T49820 WP_031336866.1 NZ_CP009790:c1779065-1778742 [Xylella fastidiosa]
MIQRGDLVTVSLQGDYGKPRPALIVQSDLLTELDSVALCPVTSDLRNAIFRVTVEPTAANGLRTLSQVMVDKISTLPRNK
ISEPFGRLNDERMKAIERALLLIIGII
MIQRGDLVTVSLQGDYGKPRPALIVQSDLLTELDSVALCPVTSDLRNAIFRVTVEPTAANGLRTLSQVMVDKISTLPRNK
ISEPFGRLNDERMKAIERALLLIIGII
Download Length: 324 bp
>T49820 NZ_CP009790:c1779065-1778742 [Xylella fastidiosa]
ATGATTCAACGTGGCGACCTTGTAACAGTTTCCCTACAAGGCGACTACGGCAAGCCTAGACCAGCGTTGATCGTTCAATC
AGACCTTCTAACGGAGTTAGATAGTGTCGCACTGTGTCCGGTCACGAGCGACCTGCGGAATGCGATATTTCGTGTCACCG
TTGAACCAACTGCGGCCAATGGTTTACGGACACTGTCGCAGGTCATGGTAGATAAAATTTCAACACTACCACGTAACAAA
ATCAGCGAACCTTTTGGACGTCTCAATGACGAGAGAATGAAAGCAATAGAAAGAGCATTGTTACTAATTATTGGTATCAT
TTAA
ATGATTCAACGTGGCGACCTTGTAACAGTTTCCCTACAAGGCGACTACGGCAAGCCTAGACCAGCGTTGATCGTTCAATC
AGACCTTCTAACGGAGTTAGATAGTGTCGCACTGTGTCCGGTCACGAGCGACCTGCGGAATGCGATATTTCGTGTCACCG
TTGAACCAACTGCGGCCAATGGTTTACGGACACTGTCGCAGGTCATGGTAGATAAAATTTCAACACTACCACGTAACAAA
ATCAGCGAACCTTTTGGACGTCTCAATGACGAGAGAATGAAAGCAATAGAAAGAGCATTGTTACTAATTATTGGTATCAT
TTAA
Antitoxin
Download Length: 74 a.a. Molecular weight: 8426.53 Da Isoelectric Point: 7.3606
>AT49820 WP_010894329.1 NZ_CP009790:c1779283-1779062 [Xylella fastidiosa]
MTSTHRPDSKIVHHREQMRAAGLRPVQLWVPDTRTPEFAAEIQSQCRALKGDQAEADALRFTEKAMTHIEDWK
MTSTHRPDSKIVHHREQMRAAGLRPVQLWVPDTRTPEFAAEIQSQCRALKGDQAEADALRFTEKAMTHIEDWK
Download Length: 222 bp
>AT49820 NZ_CP009790:c1779283-1779062 [Xylella fastidiosa]
ATGACATCAACTCACAGACCAGACAGCAAGATAGTTCACCACAGGGAACAAATGCGCGCAGCTGGATTGCGTCCTGTGCA
GCTCTGGGTACCGGATACGCGCACACCGGAATTCGCTGCTGAAATTCAAAGCCAGTGCCGCGCCCTGAAAGGCGACCAGG
CAGAAGCCGACGCTTTACGCTTCACAGAAAAAGCCATGACCCATATTGAAGATTGGAAATGA
ATGACATCAACTCACAGACCAGACAGCAAGATAGTTCACCACAGGGAACAAATGCGCGCAGCTGGATTGCGTCCTGTGCA
GCTCTGGGTACCGGATACGCGCACACCGGAATTCGCTGCTGAAATTCAAAGCCAGTGCCGCGCCCTGAAAGGCGACCAGG
CAGAAGCCGACGCTTTACGCTTCACAGAAAAAGCCATGACCCATATTGAAGATTGGAAATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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