Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1961557..1961739 Replicon chromosome
Accession NZ_CP009423
Organism Staphylococcus aureus strain USA300_SUR1

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag LG33_RS15775 Protein ID WP_001801861.1
Coordinates 1961557..1961652 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1961680..1961739 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LG33_RS10095 1957217..1957843 + 627 Protein_1897 hypothetical protein -
LG33_RS10100 1957884..1958228 + 345 WP_000627551.1 DUF3969 family protein -
LG33_RS10105 1958326..1958877 + 552 WP_000414205.1 hypothetical protein -
LG33_RS10110 1959095..1959736 - 642 WP_000494956.1 ImmA/IrrE family metallo-endopeptidase -
LG33_RS10115 1959850..1960035 - 186 WP_000809857.1 hypothetical protein -
LG33_RS10120 1960037..1960213 - 177 WP_000375476.1 hypothetical protein -
LG33_RS10125 1960224..1960607 - 384 WP_000070811.1 hypothetical protein -
LG33_RS15675 1961211..1961354 - 144 WP_001549059.1 transposase -
LG33_RS15775 1961557..1961652 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1961680..1961739 - 60 - - Antitoxin
LG33_RS10140 1961775..1961876 + 102 WP_001791893.1 hypothetical protein -
LG33_RS10145 1961854..1962030 - 177 Protein_1907 transposase -
LG33_RS10150 1962224..1962601 - 378 WP_001037045.1 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA 1954657..1994828 40171


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T48856 WP_001801861.1 NZ_CP009423:1961557-1961652 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T48856 NZ_CP009423:1961557-1961652 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 60 bp

>AT48856 NZ_CP009423:c1961739-1961680 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References