Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | sprA1-sprA1AS/- |
Location | 1961557..1961739 | Replicon | chromosome |
Accession | NZ_CP009423 | ||
Organism | Staphylococcus aureus strain USA300_SUR1 |
Toxin (Protein)
Gene name | sprA1 | Uniprot ID | - |
Locus tag | LG33_RS15775 | Protein ID | WP_001801861.1 |
Coordinates | 1961557..1961652 (+) | Length | 32 a.a. |
Antitoxin (RNA)
Gene name | sprA1AS | ||
Locus tag | - | ||
Coordinates | 1961680..1961739 (-) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
LG33_RS10095 | 1957217..1957843 | + | 627 | Protein_1897 | hypothetical protein | - |
LG33_RS10100 | 1957884..1958228 | + | 345 | WP_000627551.1 | DUF3969 family protein | - |
LG33_RS10105 | 1958326..1958877 | + | 552 | WP_000414205.1 | hypothetical protein | - |
LG33_RS10110 | 1959095..1959736 | - | 642 | WP_000494956.1 | ImmA/IrrE family metallo-endopeptidase | - |
LG33_RS10115 | 1959850..1960035 | - | 186 | WP_000809857.1 | hypothetical protein | - |
LG33_RS10120 | 1960037..1960213 | - | 177 | WP_000375476.1 | hypothetical protein | - |
LG33_RS10125 | 1960224..1960607 | - | 384 | WP_000070811.1 | hypothetical protein | - |
LG33_RS15675 | 1961211..1961354 | - | 144 | WP_001549059.1 | transposase | - |
LG33_RS15775 | 1961557..1961652 | + | 96 | WP_001801861.1 | type I toxin-antitoxin system Fst family toxin PepA1 | Toxin |
- | 1961680..1961739 | - | 60 | - | - | Antitoxin |
LG33_RS10140 | 1961775..1961876 | + | 102 | WP_001791893.1 | hypothetical protein | - |
LG33_RS10145 | 1961854..1962030 | - | 177 | Protein_1907 | transposase | - |
LG33_RS10150 | 1962224..1962601 | - | 378 | WP_001037045.1 | DUF1433 domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
inside | Prophage | - | lukD / hlgA | 1954657..1994828 | 40171 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 32 a.a. Molecular weight: 3554.32 Da Isoelectric Point: 10.4449
>T48856 WP_001801861.1 NZ_CP009423:1961557-1961652 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK
Download Length: 96 bp
>T48856 NZ_CP009423:1961557-1961652 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG
Antitoxin
Download Length: 60 bp
>AT48856 NZ_CP009423:c1961739-1961680 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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