Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2007056..2007324 Replicon chromosome
Accession NZ_CP007799
Organism Escherichia coli Nissle 1917

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2007094..2007196 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2007056..2007324 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ECOLIN_RS10215 (ECOLIN_09850) 2004213..2005652 + 1440 WP_001704100.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
ECOLIN_RS10220 (ECOLIN_09855) 2005770..2006006 + 237 WP_001295499.1 DUF1480 family protein -
ECOLIN_RS10225 (ECOLIN_09860) 2006111..2006302 + 192 WP_001317886.1 YebW family protein -
ECOLIN_RS10230 (ECOLIN_09865) 2006303..2006959 - 657 WP_000812743.1 protein-serine/threonine phosphatase -
- 2007056..2007324 + 269 - - Antitoxin
- 2007094..2007196 - 103 - - Toxin
ECOLIN_RS10240 (ECOLIN_09875) 2007354..2007695 - 342 WP_000984819.1 YebY family protein -
ECOLIN_RS10245 (ECOLIN_09880) 2007708..2008580 - 873 WP_000879311.1 copper homeostasis membrane protein CopD -
ECOLIN_RS10250 (ECOLIN_09885) 2008584..2008958 - 375 WP_000168747.1 CopC domain-containing protein YobA -
ECOLIN_RS10255 (ECOLIN_09890) 2009097..2009327 + 231 WP_000916763.1 DNA polymerase III subunit theta -
ECOLIN_RS10260 (ECOLIN_09895) 2009430..2010086 + 657 WP_000011644.1 carbon-nitrogen hydrolase family protein -
ECOLIN_RS10265 (ECOLIN_09900) 2010110..2010772 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2004207..2079177 74970


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences

Toxin        


Download         Length: 103 bp

>T47033 NZ_CP007799:c2007196-2007094 [Escherichia coli Nissle 1917]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT47033 NZ_CP007799:2007056-2007324 [Escherichia coli Nissle 1917]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures

Antitoxin

Download structure file

Antitoxin

Download structure file

References