Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1910887..1911069 Replicon chromosome
Accession NZ_CP007670
Organism Staphylococcus aureus strain M121

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag EP54_RS17000 Protein ID WP_001801861.1
Coordinates 1910887..1910982 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1911010..1911069 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EP54_RS09470 1906547..1907173 + 627 WP_000669046.1 hypothetical protein -
EP54_RS09475 1907214..1907558 + 345 WP_000627551.1 DUF3969 family protein -
EP54_RS09480 1907656..1908207 + 552 WP_000414205.1 hypothetical protein -
EP54_RS09485 1908425..1909066 - 642 WP_000494956.1 ImmA/IrrE family metallo-endopeptidase -
EP54_RS09490 1909180..1909365 - 186 WP_000809857.1 hypothetical protein -
EP54_RS16145 1909367..1909543 - 177 WP_000375476.1 hypothetical protein -
EP54_RS09500 1909554..1909937 - 384 WP_000070811.1 hypothetical protein -
EP54_RS16155 1910541..1910684 - 144 WP_001549059.1 transposase -
EP54_RS17000 1910887..1910982 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1911010..1911069 - 60 - - Antitoxin
EP54_RS16160 1911105..1911206 + 102 WP_001791893.1 hypothetical protein -
EP54_RS16165 1911184..1911360 - 177 Protein_1825 transposase -
EP54_RS09520 1911554..1911931 - 378 WP_001037045.1 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA 1903987..1944157 40170


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T46822 WP_001801861.1 NZ_CP007670:1910887-1910982 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T46822 NZ_CP007670:1910887-1910982 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 60 bp

>AT46822 NZ_CP007670:c1911069-1911010 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References