Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | bsrE-as-bsrE/- |
Location | 2010436..2010682 | Replicon | chromosome |
Accession | NZ_CP005997 | ||
Organism | Bacillus subtilis TO-A |
Toxin (Protein)
Gene name | bsrE | Uniprot ID | - |
Locus tag | M036_RS21930 | Protein ID | WP_109789044.1 |
Coordinates | 2010436..2010528 (+) | Length | 31 a.a. |
Antitoxin (RNA)
Gene name | as-bsrE | ||
Locus tag | - | ||
Coordinates | 2010509..2010682 (-) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
M036_RS10110 | 2005595..2005930 | + | 336 | WP_009967409.1 | hypothetical protein | - |
M036_RS10115 | 2005977..2009582 | - | 3606 | WP_004399367.1 | membrane protein | - |
M036_RS10120 | 2009815..2010147 | - | 333 | WP_026009814.1 | hypothetical protein | - |
M036_RS21930 | 2010436..2010528 | + | 93 | WP_109789044.1 | type I toxin-antitoxin system toxin BsrE | Toxin |
- | 2010509..2010682 | - | 174 | - | - | Antitoxin |
M036_RS10125 | 2010797..2011639 | - | 843 | WP_003231327.1 | hypothetical protein | - |
M036_RS10130 | 2011839..2012297 | - | 459 | WP_003231326.1 | type II toxin-antitoxin system antitoxin YobK | - |
M036_RS10135 | 2012307..2014109 | - | 1803 | WP_004399481.1 | type II toxin-antitoxin system toxin ribonuclease YobL | - |
M036_RS10140 | 2014211..2014768 | - | 558 | WP_004399321.1 | SMI1/KNR4 family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
inside | Prophage | - | - | 1996421..2031007 | 34586 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 31 a.a. Molecular weight: 3358.16 Da Isoelectric Point: 4.1840
>T45156 WP_109789044.1 NZ_CP005997:2010436-2010528 [Bacillus subtilis TO-A]
MSTFQALMLMLAIGSFIIALLTYIEKIDLP
MSTFQALMLMLAIGSFIIALLTYIEKIDLP
Download Length: 93 bp
>T45156 NZ_CP005997:2010436-2010528 [Bacillus subtilis TO-A]
ATGTCAACATTCCAGGCATTAATGCTAATGCTTGCAATCGGGTCGTTTATAATCGCCCTATTGACGTATATAGAAAAAAT
AGACCTCCCTTGA
ATGTCAACATTCCAGGCATTAATGCTAATGCTTGCAATCGGGTCGTTTATAATCGCCCTATTGACGTATATAGAAAAAAT
AGACCTCCCTTGA
Antitoxin
Download Length: 174 bp
>AT45156 NZ_CP005997:c2010682-2010509 [Bacillus subtilis TO-A]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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