Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) bsrE-as-bsrE/-
Location 2010436..2010682 Replicon chromosome
Accession NZ_CP005997
Organism Bacillus subtilis TO-A

Toxin (Protein)


Gene name bsrE Uniprot ID -
Locus tag M036_RS21930 Protein ID WP_109789044.1
Coordinates 2010436..2010528 (+) Length 31 a.a.

Antitoxin (RNA)


Gene name as-bsrE
Locus tag -
Coordinates 2010509..2010682 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M036_RS10110 2005595..2005930 + 336 WP_009967409.1 hypothetical protein -
M036_RS10115 2005977..2009582 - 3606 WP_004399367.1 membrane protein -
M036_RS10120 2009815..2010147 - 333 WP_026009814.1 hypothetical protein -
M036_RS21930 2010436..2010528 + 93 WP_109789044.1 type I toxin-antitoxin system toxin BsrE Toxin
- 2010509..2010682 - 174 - - Antitoxin
M036_RS10125 2010797..2011639 - 843 WP_003231327.1 hypothetical protein -
M036_RS10130 2011839..2012297 - 459 WP_003231326.1 type II toxin-antitoxin system antitoxin YobK -
M036_RS10135 2012307..2014109 - 1803 WP_004399481.1 type II toxin-antitoxin system toxin ribonuclease YobL -
M036_RS10140 2014211..2014768 - 558 WP_004399321.1 SMI1/KNR4 family protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 1996421..2031007 34586


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(1-24)


Sequences


Toxin        


Download         Length: 31 a.a.        Molecular weight: 3358.16 Da        Isoelectric Point: 4.1840

>T45156 WP_109789044.1 NZ_CP005997:2010436-2010528 [Bacillus subtilis TO-A]
MSTFQALMLMLAIGSFIIALLTYIEKIDLP

Download         Length: 93 bp

>T45156 NZ_CP005997:2010436-2010528 [Bacillus subtilis TO-A]
ATGTCAACATTCCAGGCATTAATGCTAATGCTTGCAATCGGGTCGTTTATAATCGCCCTATTGACGTATATAGAAAAAAT
AGACCTCCCTTGA

Antitoxin


Download         Length: 174 bp

>AT45156 NZ_CP005997:c2010682-2010509 [Bacillus subtilis TO-A]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References