Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | txpA-MW1433/- |
Location | 2090264..2090571 | Replicon | chromosome |
Accession | NZ_AP024742 | ||
Organism | Staphylococcus aureus strain 59736 |
Toxin (Protein)
Gene name | txpA | Uniprot ID | Q2FWU9 |
Locus tag | OCX51_RS10390 | Protein ID | WP_011447039.1 |
Coordinates | 2090395..2090571 (-) | Length | 59 a.a. |
Antitoxin (RNA)
Gene name | MW1433 | ||
Locus tag | - | ||
Coordinates | 2090264..2090403 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
OCX51_RS10345 (2085264) | 2085264..2085461 | + | 198 | WP_000239610.1 | phospholipase | - |
OCX51_RS10350 (2085833) | 2085833..2086012 | + | 180 | WP_000669791.1 | hypothetical protein | - |
OCX51_RS10355 (2086323) | 2086323..2086583 | + | 261 | WP_001791826.1 | hypothetical protein | - |
OCX51_RS10360 (2086636) | 2086636..2086986 | - | 351 | WP_000702263.1 | complement inhibitor SCIN-A | - |
OCX51_RS10365 (2087498) | 2087498..2087833 | - | 336 | Protein_2004 | SH3 domain-containing protein | - |
OCX51_RS10370 (2088484) | 2088484..2088975 | - | 492 | WP_000920038.1 | staphylokinase | - |
OCX51_RS10375 (2089166) | 2089166..2089921 | - | 756 | WP_000861038.1 | CHAP domain-containing protein | - |
OCX51_RS10380 (2089933) | 2089933..2090187 | - | 255 | WP_000611512.1 | phage holin | - |
OCX51_RS10385 (2090235) | 2090235..2090342 | + | 108 | WP_031762631.1 | hypothetical protein | - |
- (2090264) | 2090264..2090403 | + | 140 | NuclAT_0 | - | Antitoxin |
- (2090264) | 2090264..2090403 | + | 140 | NuclAT_0 | - | Antitoxin |
- (2090264) | 2090264..2090403 | + | 140 | NuclAT_0 | - | Antitoxin |
- (2090264) | 2090264..2090403 | + | 140 | NuclAT_0 | - | Antitoxin |
OCX51_RS10390 (2090395) | 2090395..2090571 | - | 177 | WP_011447039.1 | type I toxin-antitoxin system toxin PepG1 | Toxin |
OCX51_RS10395 (2090680) | 2090680..2091453 | - | 774 | WP_000750412.1 | staphylococcal enterotoxin type A | - |
OCX51_RS10400 (2091826) | 2091826..2092200 | - | 375 | WP_000340977.1 | hypothetical protein | - |
OCX51_RS10405 (2092256) | 2092256..2092543 | - | 288 | WP_001262621.1 | hypothetical protein | - |
OCX51_RS10410 (2092589) | 2092589..2092741 | - | 153 | WP_001000058.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
inside | Prophage | - | scn / sak / sea / selq / selk / hlb / groEL | 2086636..2145150 | 58514 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 59 a.a. Molecular weight: 6849.45 Da Isoelectric Point: 10.6777
>T39410 WP_011447039.1 NZ_AP024742:c2090571-2090395 [Staphylococcus aureus]
MDRWWLSEYKEVVPMVALLKSLERRRLMITISTMLQFGLFLIALIGLVIKLIELSNKK
MDRWWLSEYKEVVPMVALLKSLERRRLMITISTMLQFGLFLIALIGLVIKLIELSNKK
Download Length: 177 bp
>T39410 NZ_AP024742:c2090571-2090395 [Staphylococcus aureus]
TTGGATAGATGGTGGCTATCTGAGTATAAGGAGGTGGTGCCTATGGTGGCATTACTGAAATCTTTAGAAAGGAGACGCCT
AATGATTACAATTAGTACCATGTTGCAGTTTGGTTTATTCCTTATTGCATTGATAGGTCTAGTAATCAAGCTTATTGAAT
TAAGCAATAAAAAATAA
TTGGATAGATGGTGGCTATCTGAGTATAAGGAGGTGGTGCCTATGGTGGCATTACTGAAATCTTTAGAAAGGAGACGCCT
AATGATTACAATTAGTACCATGTTGCAGTTTGGTTTATTCCTTATTGCATTGATAGGTCTAGTAATCAAGCTTATTGAAT
TAAGCAATAAAAAATAA
Antitoxin
Download Length: 140 bp
>AT39410 NZ_AP024742:2090264-2090403 [Staphylococcus aureus]
ATATATAGAAAAAGGGCAACATGCGCAAACATGTTACCCTAGTGAGCCCGTTAAAAAGACGGTGGCTATTTTAGATTAAA
GATTAAATTAATAACCATTTAACCATCGAAACCAGCCAAAGTTAGCGATGGTTATTTTTT
ATATATAGAAAAAGGGCAACATGCGCAAACATGTTACCCTAGTGAGCCCGTTAAAAAGACGGTGGCTATTTTAGATTAAA
GATTAAATTAATAACCATTTAACCATCGAAACCAGCCAAAGTTAGCGATGGTTATTTTTT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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