Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1931507..1931689 Replicon chromosome
Accession NZ_AP024742
Organism Staphylococcus aureus strain 59736

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag OCX51_RS09415 Protein ID WP_001801861.1
Coordinates 1931507..1931602 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1931630..1931689 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCX51_RS09380 1927177..1927803 + 627 WP_000669017.1 hypothetical protein -
OCX51_RS09385 1927844..1928185 + 342 WP_000627541.1 DUF3969 family protein -
OCX51_RS09390 1928286..1928858 + 573 WP_000414202.1 hypothetical protein -
OCX51_RS09395 1929056..1929684 - 629 Protein_1849 ImmA/IrrE family metallo-endopeptidase -
OCX51_RS09400 1929987..1930163 - 177 WP_000375477.1 hypothetical protein -
OCX51_RS09405 1930174..1930557 - 384 Protein_1851 hypothetical protein -
OCX51_RS09410 1931161..1931304 - 144 WP_001549059.1 transposase -
OCX51_RS09415 1931507..1931602 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1931630..1931689 - 60 - - Antitoxin
OCX51_RS09420 1931725..1931826 + 102 WP_001791893.1 hypothetical protein -
OCX51_RS09425 1931804..1931980 - 177 Protein_1855 transposase -
OCX51_RS09430 1932174..1932551 - 378 WP_001037045.1 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA 1924826..1964793 39967


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T39407 WP_001801861.1 NZ_AP024742:1931507-1931602 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T39407 NZ_AP024742:1931507-1931602 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 60 bp

>AT39407 NZ_AP024742:c1931689-1931630 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References