39390

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-MW1433/-
Location 2087059..2087366 Replicon chromosome
Accession NZ_AP024738
Organism Staphylococcus aureus strain 59731

Toxin (Protein)


Gene name txpA Uniprot ID Q2FWU9
Locus tag OCX20_RS10375 Protein ID WP_011447039.1
Coordinates 2087190..2087366 (-) Length 59 a.a.

Antitoxin (RNA)


Gene name MW1433
Locus tag -
Coordinates 2087059..2087198 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCX20_RS10330 (2082059) 2082059..2082256 + 198 WP_000239610.1 phospholipase -
OCX20_RS10335 (2082628) 2082628..2082807 + 180 WP_000669791.1 hypothetical protein -
OCX20_RS10340 (2083118) 2083118..2083378 + 261 WP_001791826.1 hypothetical protein -
OCX20_RS10345 (2083431) 2083431..2083781 - 351 WP_000702263.1 complement inhibitor SCIN-A -
OCX20_RS10350 (2084293) 2084293..2084628 - 336 Protein_2002 SH3 domain-containing protein -
OCX20_RS10355 (2085279) 2085279..2085770 - 492 WP_000920038.1 staphylokinase -
OCX20_RS10360 (2085961) 2085961..2086716 - 756 WP_000861038.1 CHAP domain-containing protein -
OCX20_RS10365 (2086728) 2086728..2086982 - 255 WP_000611512.1 phage holin -
OCX20_RS10370 (2087030) 2087030..2087137 + 108 WP_031762631.1 hypothetical protein -
- (2087059) 2087059..2087198 + 140 NuclAT_0 - Antitoxin
- (2087059) 2087059..2087198 + 140 NuclAT_0 - Antitoxin
- (2087059) 2087059..2087198 + 140 NuclAT_0 - Antitoxin
- (2087059) 2087059..2087198 + 140 NuclAT_0 - Antitoxin
OCX20_RS10375 (2087190) 2087190..2087366 - 177 WP_011447039.1 type I toxin-antitoxin system toxin PepG1 Toxin
OCX20_RS10380 (2087475) 2087475..2088248 - 774 WP_000750412.1 staphylococcal enterotoxin type A -
OCX20_RS10385 (2088621) 2088621..2088995 - 375 WP_000340977.1 hypothetical protein -
OCX20_RS10390 (2089051) 2089051..2089338 - 288 WP_001262621.1 hypothetical protein -
OCX20_RS10395 (2089384) 2089384..2089536 - 153 WP_001000058.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - scn / sak / sea / selq / selk / hlb / groEL 2083431..2138919 55488


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(30-58)


Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6849.45 Da        Isoelectric Point: 10.6777

>T39390 WP_011447039.1 NZ_AP024738:c2087366-2087190 [Staphylococcus aureus]
MDRWWLSEYKEVVPMVALLKSLERRRLMITISTMLQFGLFLIALIGLVIKLIELSNKK

Download         Length: 177 bp

>T39390 NZ_AP024738:c2087366-2087190 [Staphylococcus aureus]
TTGGATAGATGGTGGCTATCTGAGTATAAGGAGGTGGTGCCTATGGTGGCATTACTGAAATCTTTAGAAAGGAGACGCCT
AATGATTACAATTAGTACCATGTTGCAGTTTGGTTTATTCCTTATTGCATTGATAGGTCTAGTAATCAAGCTTATTGAAT
TAAGCAATAAAAAATAA

Antitoxin


Download         Length: 140 bp

>AT39390 NZ_AP024738:2087059-2087198 [Staphylococcus aureus]
ATATATAGAAAAAGGGCAACATGCGCAAACATGTTACCCTAGTGAGCCCGTTAAAAAGACGGTGGCTATTTTAGATTAAA
GATTAAATTAATAACCATTTAACCATCGAAACCAGCCAAAGTTAGCGATGGTTATTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 7NS1

Antitoxin

Download structure file

References