Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | txpA-SprF1/- |
Location | 2038173..2038480 | Replicon | chromosome |
Accession | NZ_AP024732 | ||
Organism | Staphylococcus aureus strain 59621 |
Toxin (Protein)
Gene name | txpA | Uniprot ID | Q2FWU9 |
Locus tag | OCX17_RS10070 | Protein ID | WP_011447039.1 |
Coordinates | 2038304..2038480 (-) | Length | 59 a.a. |
Antitoxin (RNA)
Gene name | SprF1 | ||
Locus tag | - | ||
Coordinates | 2038173..2038312 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
OCX17_RS10025 (2033173) | 2033173..2033370 | + | 198 | WP_000239610.1 | phospholipase | - |
OCX17_RS10030 (2033742) | 2033742..2033921 | + | 180 | WP_000669791.1 | hypothetical protein | - |
OCX17_RS10035 (2034232) | 2034232..2034492 | + | 261 | WP_001791826.1 | hypothetical protein | - |
OCX17_RS10040 (2034545) | 2034545..2034895 | - | 351 | WP_000702263.1 | complement inhibitor SCIN-A | - |
OCX17_RS10045 (2035407) | 2035407..2035742 | - | 336 | Protein_1940 | SH3 domain-containing protein | - |
OCX17_RS10050 (2036393) | 2036393..2036884 | - | 492 | WP_000920038.1 | staphylokinase | - |
OCX17_RS10055 (2037075) | 2037075..2037830 | - | 756 | WP_000861038.1 | CHAP domain-containing protein | - |
OCX17_RS10060 (2037842) | 2037842..2038096 | - | 255 | WP_000611512.1 | phage holin | - |
OCX17_RS10065 (2038144) | 2038144..2038251 | + | 108 | WP_031762631.1 | hypothetical protein | - |
- (2038173) | 2038173..2038312 | + | 140 | NuclAT_0 | - | Antitoxin |
- (2038173) | 2038173..2038312 | + | 140 | NuclAT_0 | - | Antitoxin |
- (2038173) | 2038173..2038312 | + | 140 | NuclAT_0 | - | Antitoxin |
- (2038173) | 2038173..2038312 | + | 140 | NuclAT_0 | - | Antitoxin |
OCX17_RS10070 (2038304) | 2038304..2038480 | - | 177 | WP_011447039.1 | type I toxin-antitoxin system toxin PepG1 | Toxin |
OCX17_RS10075 (2038589) | 2038589..2039362 | - | 774 | WP_000750412.1 | staphylococcal enterotoxin type A | - |
OCX17_RS10080 (2039735) | 2039735..2040109 | - | 375 | WP_000340977.1 | hypothetical protein | - |
OCX17_RS10085 (2040165) | 2040165..2040452 | - | 288 | WP_001262621.1 | hypothetical protein | - |
OCX17_RS10090 (2040498) | 2040498..2040650 | - | 153 | WP_001000058.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
inside | Prophage | - | scn / sak / sea / selq / selk / hlb / groEL | 2034545..2093022 | 58477 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 59 a.a. Molecular weight: 6849.45 Da Isoelectric Point: 10.6777
>T39330 WP_011447039.1 NZ_AP024732:c2038480-2038304 [Staphylococcus aureus]
MDRWWLSEYKEVVPMVALLKSLERRRLMITISTMLQFGLFLIALIGLVIKLIELSNKK
MDRWWLSEYKEVVPMVALLKSLERRRLMITISTMLQFGLFLIALIGLVIKLIELSNKK
Download Length: 177 bp
>T39330 NZ_AP024732:c2038480-2038304 [Staphylococcus aureus]
TTGGATAGATGGTGGCTATCTGAGTATAAGGAGGTGGTGCCTATGGTGGCATTACTGAAATCTTTAGAAAGGAGACGCCT
AATGATTACAATTAGTACCATGTTGCAGTTTGGTTTATTCCTTATTGCATTGATAGGTCTAGTAATCAAGCTTATTGAAT
TAAGCAATAAAAAATAA
TTGGATAGATGGTGGCTATCTGAGTATAAGGAGGTGGTGCCTATGGTGGCATTACTGAAATCTTTAGAAAGGAGACGCCT
AATGATTACAATTAGTACCATGTTGCAGTTTGGTTTATTCCTTATTGCATTGATAGGTCTAGTAATCAAGCTTATTGAAT
TAAGCAATAAAAAATAA
Antitoxin
Download Length: 140 bp
>AT39330 NZ_AP024732:2038173-2038312 [Staphylococcus aureus]
ATATATAGAAAAAGGGCAACATGCGCAAACATGTTACCCTAGTGAGCCCGTTAAAAAGACGGTGGCTATTTTAGATTAAA
GATTAAATTAATAACCATTTAACCATCGAAACCAGCCAAAGTTAGCGATGGTTATTTTTT
ATATATAGAAAAAGGGCAACATGCGCAAACATGTTACCCTAGTGAGCCCGTTAAAAAGACGGTGGCTATTTTAGATTAAA
GATTAAATTAATAACCATTTAACCATCGAAACCAGCCAAAGTTAGCGATGGTTATTTTTT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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