Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1927067..1927249 Replicon chromosome
Accession NZ_AP024723
Organism Staphylococcus aureus strain 59458

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag OCX22_RS09405 Protein ID WP_001801861.1
Coordinates 1927067..1927162 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1927190..1927249 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCX22_RS09365 1922738..1923364 + 627 WP_000669017.1 hypothetical protein -
OCX22_RS09370 1923405..1923746 + 342 WP_000627541.1 DUF3969 family protein -
OCX22_RS09375 1923847..1924419 + 573 WP_000414202.1 hypothetical protein -
OCX22_RS09380 1924617..1925245 - 629 Protein_1846 ImmA/IrrE family metallo-endopeptidase -
OCX22_RS09385 1925360..1925545 - 186 WP_261921410.1 hypothetical protein -
OCX22_RS09390 1925547..1925723 - 177 WP_000375477.1 hypothetical protein -
OCX22_RS09395 1925734..1926117 - 384 Protein_1849 hypothetical protein -
OCX22_RS09400 1926721..1926864 - 144 WP_001549059.1 transposase -
OCX22_RS09405 1927067..1927162 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1927190..1927249 - 60 - - Antitoxin
OCX22_RS09410 1927285..1927386 + 102 WP_001791893.1 hypothetical protein -
OCX22_RS09415 1927364..1927540 - 177 Protein_1853 transposase -
OCX22_RS09420 1927734..1928111 - 378 WP_001037045.1 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA 1920974..1960307 39333


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T39256 WP_001801861.1 NZ_AP024723:1927067-1927162 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T39256 NZ_AP024723:1927067-1927162 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 60 bp

>AT39256 NZ_AP024723:c1927249-1927190 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References