Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2086207..2086352 Replicon chromosome
Accession NZ_AP023319
Organism Salmonella enterica subsp. enterica serovar 4[5]12:i:- strain L-4741

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2086247..2086350 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2086207..2086352 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K5619_RS10150 2082633..2083331 - 699 WP_000944282.1 exodeoxyribonuclease X -
K5619_RS10155 2083355..2084011 - 657 WP_000100258.1 carbon-nitrogen hydrolase family protein -
K5619_RS10160 2084119..2084349 - 231 WP_000856224.1 DNA polymerase III subunit theta -
K5619_RS10165 2084487..2084861 + 375 WP_000168393.1 CopC domain-containing protein YobA -
K5619_RS10170 2084862..2085737 + 876 WP_000979702.1 copper homeostasis membrane protein CopD -
K5619_RS10175 2085754..2086107 + 354 WP_000722368.1 YebY family protein -
- 2086207..2086352 - 146 - - Antitoxin
- 2086247..2086350 + 104 - - Toxin
K5619_RS10180 2086481..2087404 - 924 Protein_2000 tyrosine-type recombinase/integrase -
K5619_RS24260 2087668..2088129 - 462 Protein_2001 DNA breaking-rejoining protein -
K5619_RS10190 2088118..2088309 + 192 Protein_2002 glycoside hydrolase family 19 protein -
K5619_RS10195 2088363..2088896 + 534 WP_001050882.1 DUF2514 domain-containing protein -
K5619_RS10200 2089153..2089320 - 168 WP_000789530.1 lytic enzyme -
K5619_RS10205 2089385..2089573 - 189 WP_001521334.1 hypothetical protein -
K5619_RS10210 2089628..2089888 + 261 Protein_2006 DUF1441 family protein -
K5619_RS10215 2090103..2090447 + 345 Protein_2007 macro domain-containing protein -
K5619_RS10220 2090457..2090927 + 471 Protein_2008 tail fiber assembly protein -
K5619_RS10225 2091024..2091224 - 201 WP_010989029.1 PagK family vesicle-borne virulence factor -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - sopE2 2066210..2108547 42337


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T37582 NZ_AP023319:2086247-2086350 [Salmonella enterica subsp. enterica serovar 4,[5],12:i:-]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT37582 NZ_AP023319:c2086352-2086207 [Salmonella enterica subsp. enterica serovar 4,[5],12:i:-]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References