Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1961881..1962063 Replicon chromosome
Accession NZ_AP019751
Organism Staphylococcus aureus strain JRA307

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag FPG46_RS09825 Protein ID WP_001801861.1
Coordinates 1961881..1961976 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1962004..1962063 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FPG46_RS09775 1957551..1958177 + 627 WP_000669017.1 hypothetical protein -
FPG46_RS09780 1958218..1958559 + 342 WP_000627541.1 DUF3969 family protein -
FPG46_RS09785 1958660..1959232 + 573 WP_000414202.1 hypothetical protein -
FPG46_RS09790 1959430..1959987 - 558 Protein_1882 ImmA/IrrE family metallo-endopeptidase -
FPG46_RS09800 1960361..1960537 - 177 WP_000375477.1 hypothetical protein -
FPG46_RS09805 1960548..1960931 - 384 WP_000070811.1 hypothetical protein -
FPG46_RS09815 1961535..1961678 - 144 WP_001549059.1 transposase -
FPG46_RS09825 1961881..1961976 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1962004..1962063 - 60 - - Antitoxin
FPG46_RS09830 1962099..1962200 + 102 WP_001791893.1 hypothetical protein -
FPG46_RS09835 1962178..1962354 - 177 Protein_1888 transposase -
FPG46_RS09840 1962548..1962925 - 378 WP_001037045.1 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA 1954993..1995166 40173


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T32973 WP_001801861.1 NZ_AP019751:1961881-1961976 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T32973 NZ_AP019751:1961881-1961976 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 60 bp

>AT32973 NZ_AP019751:c1962063-1962004 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References