Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 1564529..1565095 Replicon chromosome
Accession NZ_LR698953
Organism Bifidobacterium longum isolate MGYG-HGUT-01292

Toxin (Protein)


Gene name relE Uniprot ID W6EX94
Locus tag FXZ20_RS07690 Protein ID WP_003831807.1
Coordinates 1564802..1565095 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FXZ20_RS07685 Protein ID WP_014484914.1
Coordinates 1564529..1564798 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FXZ20_RS07660 1560279..1560973 - 695 Protein_1417 response regulator transcription factor -
FXZ20_RS07665 1561099..1561614 + 516 WP_013140733.1 hypothetical protein -
FXZ20_RS07670 1561611..1562501 + 891 WP_014484913.1 hypothetical protein -
FXZ20_RS07675 1562498..1563178 + 681 WP_003829413.1 ABC transporter ATP-binding protein -
FXZ20_RS07680 1563175..1564344 + 1170 WP_012577732.1 ABC transporter permease -
FXZ20_RS07685 1564529..1564798 + 270 WP_014484914.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
FXZ20_RS07690 1564802..1565095 + 294 WP_003831807.1 type II toxin-antitoxin system YafQ family toxin Toxin
FXZ20_RS07695 1565153..1565433 + 281 Protein_1424 hypothetical protein -
FXZ20_RS07700 1565764..1566315 + 552 WP_012577735.1 RNA polymerase sigma factor -
FXZ20_RS07705 1566349..1567176 + 828 WP_012577736.1 hypothetical protein -
FXZ20_RS07710 1567308..1567934 + 627 WP_012577737.1 hypothetical protein -
FXZ20_RS07715 1567931..1568713 + 783 WP_012577738.1 hypothetical protein -
FXZ20_RS07720 1568766..1569641 + 876 WP_003829425.1 ABC transporter ATP-binding protein -
FXZ20_RS07725 1569695..1570093 + 399 WP_003829426.1 superoxide dismutase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Genomic island - - 1555544..1576902 21358


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-95)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(3-87)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11218.98 Da        Isoelectric Point: 9.7881

>T288685 WP_003831807.1 NZ_LR698953:1564802-1565095 [Bifidobacterium longum]
MLKPDYTAAFQRDIKKLKRKHTDLRPLKEVIRLVLEDTADSKEVLRRRHRAHTLTGDLNGVLECHIGNAGDWLLLWIRDD
GTAMFMRTGSHDELLGK

Download         Length: 294 bp

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9902.25 Da        Isoelectric Point: 4.7872

>AT288685 WP_014484914.1 NZ_LR698953:1564529-1564798 [Bifidobacterium longum]
VSMASVTVRVDADTKQKAANIAEDLGLDLSSVTRAFYKQIVRERRIPLNLSYTTVPPETMEALDEAKNRLADGKPRFNSA
DEMFDSLVI

Download         Length: 270 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB W6EX94

Antitoxin

Source ID Structure

References