Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | sprA1-sprA1AS/- |
Location | 1903261..1903443 | Replicon | chromosome |
Accession | NZ_LR134085 | ||
Organism | Staphylococcus aureus strain NCTC12233 |
Toxin (Protein)
Gene name | sprA1 | Uniprot ID | - |
Locus tag | ELZ52_RS09670 | Protein ID | WP_001801861.1 |
Coordinates | 1903261..1903356 (+) | Length | 32 a.a. |
Antitoxin (RNA)
Gene name | sprA1AS | ||
Locus tag | - | ||
Coordinates | 1903384..1903443 (-) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
ELZ52_RS09620 | 1898921..1899547 | + | 627 | WP_000669046.1 | hypothetical protein | - |
ELZ52_RS09625 | 1899588..1899932 | + | 345 | WP_000627551.1 | DUF3969 family protein | - |
ELZ52_RS09630 | 1900030..1900581 | + | 552 | WP_000414205.1 | hypothetical protein | - |
ELZ52_RS09635 | 1900799..1901440 | - | 642 | WP_000494956.1 | ImmA/IrrE family metallo-endopeptidase | - |
ELZ52_RS09640 | 1901554..1901739 | - | 186 | WP_000809857.1 | hypothetical protein | - |
ELZ52_RS09645 | 1901741..1901917 | - | 177 | WP_000375476.1 | hypothetical protein | - |
ELZ52_RS09650 | 1901928..1902311 | - | 384 | WP_000070811.1 | hypothetical protein | - |
ELZ52_RS09660 | 1902915..1903058 | - | 144 | WP_001549059.1 | transposase | - |
ELZ52_RS09670 | 1903261..1903356 | + | 96 | WP_001801861.1 | type I toxin-antitoxin system Fst family toxin PepA1 | Toxin |
- | 1903384..1903443 | - | 60 | - | - | Antitoxin |
ELZ52_RS09675 | 1903479..1903580 | + | 102 | WP_001791893.1 | hypothetical protein | - |
ELZ52_RS09680 | 1903558..1903734 | - | 177 | Protein_1815 | transposase | - |
ELZ52_RS09685 | 1903928..1904305 | - | 378 | WP_001037045.1 | DUF1433 domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
inside | Prophage | - | lukD / hlgA | 1896361..1936533 | 40172 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 32 a.a. Molecular weight: 3554.32 Da Isoelectric Point: 10.4449
>T286689 WP_001801861.1 NZ_LR134085:1903261-1903356 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK
Download Length: 96 bp
Antitoxin
Download Length: 60 bp
>AT286689 NZ_LR134085:c1903443-1903384 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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