Detailed information of TA system TA284502

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): IasE-IsrA/-
• Location: 3635566..3635986
• Replicon: chromosome
• Accession: NZ_CP128261
• Organism: Salmonella enterica subsp. enterica serovar Heidelberg isolate FT3-7B

Toxin (Protein)

• Gene name: IasE
• Uniprot ID: A0A8E7RAJ3
• Locus tag: QR684_RS17865
• Protein ID: WP_000994215.1
• Coordinates: 3635723..3635986 (+)
• Length: 88 a.a.

Antitoxin (RNA)

Gene name	IsrA
Locus tag	-
Coordinates	3635566..3635976 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QR684_RS17825	3631139..3631657	-	519	WP_001056552.1	fimbrial protein TcfB	-
QR684_RS17830	3631765..3632475	-	711	WP_001009508.1	fimbrial chaperone TcfA	-
QR684_RS17835	3633511..3634068	+	558	Protein_3487	ATP-binding protein	-
QR684_RS17840	3634108..3634294	-	187	Protein_3488	transposase	-
QR684_RS17845	3634347..3634520	+	174	WP_001531381.1	hypothetical protein	-
QR684_RS17850	3634585..3635052	-	468	WP_001284951.1	Imm42 family immunity protein	-
QR684_RS17855	3635045..3635353	-	309	WP_165488057.1	hypothetical protein	-
QR684_RS17860	3635344..3635481	-	138	WP_231391191.1	hypothetical protein	-
-	3635566..3635976	-	411	-	-	Antitoxin
QR684_RS17865	3635723..3635986	+	264	WP_000994215.1	hypothetical protein	Toxin
QR684_RS17870	3636033..3636467	-	435	WP_000789494.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	3625896..3659018	33122
	-	flank	IS/Tn	-	-	3633691..3634068	377

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 88 a.a.
• Molecular weight: 9458.71 Da
• Isoelectric Point: 6.4458

>T284502 WP_000994215.1 NZ_CP128261:3635723-3635986 [Salmonella enterica subsp. enterica serovar Heidelberg]
MNASGASVRHINSETCMTTCYSQIPSGDCQEEAGFETGASVVVKISERGLILIAETDEVRDLRKELYQVKKSMKHIKAGV
NNVVNGN

Nucleotide

• Length: 264 bp

Antitoxin

Nucleotide

• Length: 411 bp

>AT284502 NZ_CP128261:c3635976-3635566 [Salmonella enterica subsp. enterica serovar Heidelberg]
TTCACCACATTATTTACCCCCGCCTTAATATGCTTCATCGACTTTTTCACCTGATAAAGCTCCTTCCGTAGATCCCTCAC
TTCATCCGTTTCTGCAATCAGGATCAAACCCCGCTCGGAGATCTTCACAACAACGCTCGCCCCGGTCTCAAATCCCGCTT
CTTCCTGGCAGTCGCCGCTGGGGATTTGTGAGTAACAGGTGGTCATGCAGGTTTCGCTGTTGATGTGGCGGACGCTGGCG
CCGGAGGCATTCATATTTGCTGACTAAATAAATTCTTAATTCTCCGCCGGATGCTGGCTGATTGTGGAGCTCAGGGTGAG
CGAGTATGGGCGCGACATCCTGGCACTGAGCCCCCCTCTCCCCGGCCAGCTCCGGGCGGTGATGAGCAACCGGCTGCCGG
GGCCGTATTTT

Structures

Antitoxin