Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) IasE-IsrA/-
Location 3569216..3569618 Replicon chromosome
Accession NZ_CP126323
Organism Salmonella enterica subsp. enterica strain CY16

Toxin (Protein)


Gene name IasE Uniprot ID -
Locus tag QN087_RS17205 Protein ID WP_023209683.1
Coordinates 3569490..3569618 (+) Length 43 a.a.

Antitoxin (RNA)


Gene name IsrA
Locus tag -
Coordinates 3569216..3569568 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QN087_RS17170 3564618..3565115 - 498 WP_001030293.1 hypothetical protein -
QN087_RS17175 3565737..3566441 - 705 Protein_3370 integrase core domain-containing protein -
QN087_RS17180 3566494..3566742 + 249 WP_001746936.1 SymE family type I addiction module toxin -
QN087_RS17185 3566874..3567152 - 279 WP_077677834.1 hypothetical protein -
QN087_RS17190 3567538..3567936 - 399 WP_000828171.1 hypothetical protein -
QN087_RS17195 3568606..3568770 - 165 WP_001746938.1 hypothetical protein -
QN087_RS17200 3568806..3569039 - 234 WP_124084119.1 hypothetical protein -
- 3569216..3569568 - 353 - - Antitoxin
QN087_RS17205 3569490..3569618 + 129 WP_023209683.1 hypothetical protein Toxin
QN087_RS17210 3569701..3570021 - 321 WP_223201872.1 Imm8 family immunity protein -
QN087_RS17215 3570801..3571166 - 366 WP_000517964.1 hypothetical protein -
QN087_RS17220 3571132..3573932 - 2801 Protein_3379 RHS repeat-associated core domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3559548..3594774 35226
- flank IS/Tn - - 3565737..3566018 281


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 43 a.a.        Molecular weight: 4492.16 Da        Isoelectric Point: 4.4551

>T282757 WP_023209683.1 NZ_CP126323:3569490-3569618 [Salmonella enterica subsp. enterica]
VKISDGCIVLMADGNEVQELREQLYQAKRVVKGGEGCAGLVD

Download         Length: 129 bp


Antitoxin


Download         Length: 353 bp

>AT282757 NZ_CP126323:c3569568-3569216 [Salmonella enterica subsp. enterica]
CCTGATAAAGCTGTTCGCGCAGCTCCTGCACCTCGTTACCGTCCGCCATTAGCACAATACACCCGTCCGAAATCTTCACC
GTCACGCCGCTCCCCGGTCTCAAATCCCGCTTCTTCCTGGCAGTCGCCGCTGGGGATTTGTGAGTAACAGGTGGTCATGC
AGGTTTCGCTGTTGATGTGGCGGACGCTGGCGCCGGAGGTATTCATATTTGCTGACTAAATAAATTCTTAATTCTCCGCC
GGATGCTGGCTGATTGTGGAGCTCAGGGTGAGTGAGTATGGGCGCGACATCCTGGCACCGCGCCCCCCTCTCCCCGGCCA
GTGATGAGCAACCGGCTACCGGGGCCGTATTTT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References