Detailed information of TA system TA282564

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): CD-RCd/-
• Location: 1692914..1693128
• Replicon: chromosome
• Accession: NZ_CP126072
• Organism: Clostridioides difficile strain CDI-22

Toxin (Protein)

• Gene name: CD0956.2
• Uniprot ID: -
• Locus tag: ITI92_RS07925
• Protein ID: WP_032508407.1
• Coordinates: 1692914..1693075 (+)
• Length: 54 a.a.

Antitoxin (RNA)

Gene name	RCd10
Locus tag	-
Coordinates	1692995..1693128 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ITI92_RS07885 (1688102)	1688102..1688392	+	291	WP_021358995.1	HK97 gp10 family phage protein	-
ITI92_RS07890 (1688502)	1688502..1689308	+	807	WP_021358994.1	hypothetical protein	-
ITI92_RS07895 (1689657)	1689657..1689782	+	126	WP_021358993.1	hypothetical protein	-
ITI92_RS07900 (1689761)	1689761..1690093	+	333	WP_021358992.1	hypothetical protein	-
ITI92_RS07905 (1690086)	1690086..1690262	+	177	WP_021358991.1	hypothetical protein	-
ITI92_RS07910 (1690264)	1690264..1691574	+	1311	WP_021358990.1	phage tail sheath family protein	-
ITI92_RS07915 (1691591)	1691591..1692061	+	471	WP_003429851.1	phage tail tube protein	-
ITI92_RS07920 (1692133)	1692133..1692573	+	441	WP_003429853.1	phage portal protein	-
ITI92_RS07925 (1692914)	1692914..1693075	+	162	WP_032508407.1	hypothetical protein	Toxin
- (1692995)	1692995..1693128	-	134	NuclAT_1	-	Antitoxin
- (1692995)	1692995..1693128	-	134	NuclAT_1	-	Antitoxin
- (1692995)	1692995..1693128	-	134	NuclAT_2	-	Antitoxin
- (1693473)	1693473..1693521	-	49	NuclAT_5	-	-
- (1693473)	1693473..1693521	-	49	NuclAT_6	-	-
- (1693473)	1693473..1693521	-	49	NuclAT_8	-	-
- (1694500)	1694500..1694605	-	106	NuclAT_4	-	-
- (1694500)	1694500..1694605	-	106	NuclAT_5	-	-
- (1694500)	1694500..1694605	-	106	NuclAT_7	-	-
ITI92_RS07930 (1695068)	1695068..1695208	+	141	WP_284183820.1	hypothetical protein	-
ITI92_RS07935 (1695456)	1695456..1696016	+	561	WP_021359010.1	phage lipoprotein	-
ITI92_RS07940 (1696059)	1696059..1696628	+	570	WP_021359011.1	zinc ribbon domain protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 54 a.a.
• Molecular weight: 6120.42 Da
• Isoelectric Point: 10.8938

>T282564 WP_032508407.1 NZ_CP126072:1692914-1693075 [Clostridioides difficile]
MNNFLLNVIAGVIASLIFCIICKVFLKVKSHSTRGKSKSGWEFDFKIKFHKFK

Nucleotide

• Length: 162 bp

Antitoxin

Nucleotide

• Length: 134 bp

>AT282564 NZ_CP126072:c1693128-1692995 [Clostridioides difficile]
AAGAAGAACTACAATCTATTTTGCGGTAGAGTGAAGTTCATAATTAAATGAATCTATTTGAACTTATGGAACTTGATTTT
AAAATCAAATTCCCAGCCACTTTTACTCTTGCCACGAGTTGAGTGGCTTTTTAC

Structures

Antitoxin