Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) IasE-IsrA/SymE(toxin)
Location 3653582..3653843 Replicon chromosome
Accession NZ_CP123660
Organism Salmonella enterica subsp. enterica serovar Kentucky strain CVM N38232

Toxin (Protein)


Gene name IasE Uniprot ID -
Locus tag DE22_RS17695 Protein ID WP_022630712.1
Coordinates 3653616..3653843 (+) Length 76 a.a.

Antitoxin (RNA)


Gene name IsrA
Locus tag -
Coordinates 3653582..3653833 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DE22_RS17660 3648783..3649061 - 279 WP_077905245.1 hypothetical protein -
DE22_RS17665 3649378..3649845 - 468 WP_000828176.1 hypothetical protein -
DE22_RS17670 3649842..3650213 - 372 WP_223154463.1 hypothetical protein -
DE22_RS17675 3650717..3650950 - 234 WP_129589482.1 hypothetical protein -
DE22_RS17680 3651284..3651529 + 246 WP_000994223.1 hypothetical protein -
DE22_RS17685 3651593..3652039 - 447 WP_000171103.1 hypothetical protein -
DE22_RS17690 3652036..3653535 - 1500 Protein_3460 RHS repeat-associated core domain-containing protein -
- 3653582..3653833 - 252 - - Antitoxin
DE22_RS17695 3653616..3653843 + 228 WP_022630712.1 SymE family type I addiction module toxin Toxin
DE22_RS17700 3653890..3654324 - 435 WP_000789494.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3638491..3688013 49522


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(5-41)


Sequences


Toxin        


Download         Length: 76 a.a.        Molecular weight: 8354.60 Da        Isoelectric Point: 8.0260

>T279121 WP_022630712.1 NZ_CP123660:3653616-3653843 [Salmonella enterica subsp. enterica serovar Kentucky]
MTTYYSRIPSLHLKGDWLTEAGFDTGASVTVKISEGCLILIAETDEVRDLRKELYQVKKSMKHIKAGVNNVVNGN

Download         Length: 228 bp


Antitoxin


Download         Length: 252 bp

>AT279121 NZ_CP123660:c3653833-3653582 [Salmonella enterica subsp. enterica serovar Kentucky]
TTCACCACATTATTTACCCCCGCCTTAATATGCTTCATCGACTTTTTCACCTGATAAAGCTCCTTCCGTAAATCCCTCAC
TTCGTCCGTCTCTGCAATCAGGATCAAACACCCCTCGGAGATCTTCACTGTCACGCTCGCGCCGGTATCAAATCCCGCTT
CTGTCAGCCAGTCACCCTTGAGATGCAGGCTGGGAATGCGTGAGTAATAGGTGGTCATGTGGGTTTTGCTGTTCTCGTGG
CGGACGCTGACG

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References