Detailed information of TA system TA278907

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): IasE-IsrA/-
• Location: 3550520..3550922
• Replicon: chromosome
• Accession: NZ_CP123282
• Organism: Salmonella sp. SA14318

Toxin (Protein)

• Gene name: IasE
• Uniprot ID: A0A3V9S8T1
• Locus tag: QEN32_RS17060
• Protein ID: WP_000994223.1
• Coordinates: 3550677..3550922 (+)
• Length: 82 a.a.

Antitoxin (RNA)

Gene name	IsrA
Locus tag	-
Coordinates	3550520..3550886 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QEN32_RS17035	3545775..3546275	-	501	WP_265321986.1	pilus assembly protein	-
QEN32_RS17040	3547037..3547741	-	705	Protein_3330	integrase core domain-containing protein	-
QEN32_RS17045	3547794..3548108	+	315	WP_001539118.1	SymE family type I addiction module toxin	-
QEN32_RS17050	3548174..3548452	-	279	WP_077905245.1	hypothetical protein	-
QEN32_RS17055	3548769..3549236	-	468	WP_000828176.1	hypothetical protein	-
-	3550520..3550886	-	367	-	-	Antitoxin
QEN32_RS17060	3550677..3550922	+	246	WP_000994223.1	hypothetical protein	Toxin
QEN32_RS17065	3550986..3551432	-	447	WP_000171103.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	3547037..3547318	281
	-	inside	Prophage	-	gmhA/lpcA	3479857..3558840	78983

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 82 a.a.
• Molecular weight: 8789.96 Da
• Isoelectric Point: 4.1428

>T278907 WP_000994223.1 NZ_CP123282:3550677-3550922 [Salmonella sp. SA14318]
MNASGVSVRHINSETCMTACYSQIPSGDCQEEAGFETGRSVTVKISDGCIVLMADGNEVQKLCEQLYQAEQVVKGMWDVI
V

Nucleotide

• Length: 246 bp

Antitoxin

Nucleotide

• Length: 367 bp

>AT278907 NZ_CP123282:c3550886-3550520 [Salmonella sp. SA14318]
TTCAGCCTGATAAAGCTGTTCGCACAGCTTCTGCACCTCGTTACCGTCCGCCATTAGCACAATACACCCGTCCGAAATCT
TCACCGTCACGCTGCGCCCGGTCTCAAATCCCGCTTCTTCCTGGCAGTCGCCGCTGGGGATTTGTGAGTAACAGGCGGTC
ATGCAGGTTTCGCTGTTGATGTGGCGGACGCTGACGCCGGAGGCATTCATATTTGCTGACTAAATAAATTCTTATTTATC
CGCCGGATGCTGGCTGATTGTGGAGCTCAGGGTGAGTGAGTATGGGCGCGACATCCTGGCACTGCGCCCCCCTCTCCCCG
GCCAGCACCGGGCGGTGATGAGCAACCGGCTGCCGGGGCCGTATTTT

Structures

Toxin

• AlphaFold DB: A0A3V9S8T1

Antitoxin