Detailed information of TA system TA278883

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): IasE-IsrA/SymE(toxin)
• Location: 1995425..1995857
• Replicon: chromosome
• Accession: NZ_CP123280
• Organism: Salmonella sp. SA17155

Toxin (Protein)

• Gene name: IasE
• Uniprot ID: E8XIW0
• Locus tag: QEN30_RS10430
• Protein ID: WP_000994224.1
• Coordinates: 1995582..1995857 (+)
• Length: 92 a.a.

Antitoxin (RNA)

Gene name	IsrA
Locus tag	-
Coordinates	1995425..1995847 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QEN30_RS10400	1991643..1992380	-	738	WP_001535430.1	pili assembly chaperone SafB	-
QEN30_RS10405	1992464..1992976	-	513	WP_077248260.1	pilus assembly protein	-
QEN30_RS10410	1993726..1994430	-	705	Protein_2034	integrase core domain-containing protein	-
QEN30_RS10415	1994483..1994731	+	249	WP_001738030.1	SymE family type I addiction module toxin	-
QEN30_RS10420	1994833..1995141	-	309	WP_010988969.1	hypothetical protein	-
QEN30_RS10425	1995224..1995340	-	117	WP_227457392.1	hypothetical protein	-
-	1995425..1995847	-	423	-	-	Antitoxin
QEN30_RS10430	1995582..1995857	+	276	WP_000994224.1	SymE family type I addiction module toxin	Toxin
QEN30_RS10435	1995910..1996347	-	438	WP_000943619.1	immunity 26/phosphotriesterase HocA family protein	-
QEN30_RS10440	1996910..1997356	-	447	WP_000935097.1	protein SciX	-
QEN30_RS10445	1997350..1998219	-	870	Protein_2041	polymorphic toxin type 47 domain-containing protein	-
QEN30_RS10450	1998283..1998546	-	264	WP_000932531.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	1984573..1998546	13973
	-	flank	IS/Tn	-	-	1993726..1994007	281

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin SymE-like (14-57)

Sequences

Toxin

Protein

• Length: 92 a.a.
• Molecular weight: 10032.36 Da
• Isoelectric Point: 6.4704

>T278883 WP_000994224.1 NZ_CP123280:1995582-1995857 [Salmonella sp. SA17155]
MNASGVSVRHINSETCMTACYSQIPSQHLKGDWQEEAGFETGHGVTVKISEGCLILIAETDEVRDLRKELYQVKKSMKHI
KAGVNNVVNGD

Nucleotide

• Length: 276 bp

Antitoxin

Nucleotide

• Length: 423 bp

>AT278883 NZ_CP123280:c1995847-1995425 [Salmonella sp. SA17155]
TTCACCACATTATTTACCCCCGCCTTAATATGCTTCATCGACTTTTTCACCTGATAAAGCTCCTTCCGTAGATCCCTCAC
TTCGTCCGTCTCTGCAATCAGGATCAAACACCCCTCGGAGATCTTCACGGTGACGCCGTGCCCGGTCTCAAATCCCGCTT
CTTCCTGCCAGTCACCCTTAAGGTGCTGGCTGGGGATTTGTGAGTAACAGGCGGTCATGCAGGTTTCGCTGTTGATATGG
CGGACGCTGACGCCGGAGGCATTCATATTTGCTGACTAAATAAATTCTTATTTATCCGCCGGATGCTGGCTGATTGTGGA
GCTCAGGGTGAGTGAGTATGGGCGCGACATCCTGGCACCGCGCCTCCCTCTCCCCGGCCAGCCCCGGCCGGTGATGAGCA
GCCGGCTGCCGGGGCCGTATTTT

Structures

Toxin

• AlphaFold DB: A0A3V2JPW5

Antitoxin