Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2354218..2354363 Replicon chromosome
Accession NZ_CP121298
Organism Salmonella enterica subsp. enterica strain KKP 3080

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2354258..2354361 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2354218..2354363 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P1839_RS11235 2350644..2351342 - 699 WP_000944282.1 exodeoxyribonuclease X -
P1839_RS11240 2351366..2352022 - 657 WP_000100258.1 carbon-nitrogen hydrolase family protein -
P1839_RS11245 2352130..2352360 - 231 WP_000856224.1 DNA polymerase III subunit theta -
P1839_RS11250 2352498..2352872 + 375 WP_000168393.1 CopC domain-containing protein YobA -
P1839_RS11255 2352873..2353748 + 876 WP_000979702.1 copper homeostasis membrane protein CopD -
P1839_RS11260 2353765..2354118 + 354 WP_000722368.1 YebY family protein -
- 2354218..2354363 - 146 - - Antitoxin
- 2354258..2354361 + 104 - - Toxin
P1839_RS11265 2354492..2355415 - 924 Protein_2180 tyrosine-type recombinase/integrase -
P1839_RS11270 2355679..2356140 - 462 Protein_2181 DNA breaking-rejoining protein -
P1839_RS11275 2356129..2356320 + 192 Protein_2182 glycoside hydrolase family 19 protein -
P1839_RS11280 2356374..2356907 + 534 WP_001050882.1 DUF2514 domain-containing protein -
P1839_RS11285 2357164..2357331 - 168 WP_000789530.1 lytic enzyme -
P1839_RS11290 2357396..2357584 - 189 WP_001521334.1 hypothetical protein -
P1839_RS11295 2357639..2357899 + 261 Protein_2186 DUF1441 family protein -
P1839_RS11300 2357901..2358116 + 216 Protein_2187 shikimate transporter -
P1839_RS11305 2358114..2358458 + 345 Protein_2188 macro domain-containing protein -
P1839_RS11310 2358468..2358938 + 471 Protein_2189 tail fiber assembly protein -
P1839_RS11315 2359035..2359235 - 201 WP_010989029.1 PagK family vesicle-borne virulence factor -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - sopE2 2348558..2373940 25382


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T276257 NZ_CP121298:2354258-2354361 [Salmonella enterica subsp. enterica]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT276257 NZ_CP121298:c2354363-2354218 [Salmonella enterica subsp. enterica]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References