Detailed information of TA system TA275338

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): IasE-IsrA/-
• Location: 2927425..2927845
• Replicon: chromosome
• Accession: NZ_CP120671
• Organism: Salmonella enterica strain SC2020597

Toxin (Protein)

• Gene name: IasE
• Uniprot ID: A0A8E7RAJ3
• Locus tag: P4B13_RS13910
• Protein ID: WP_000994215.1
• Coordinates: 2927425..2927688 (-)
• Length: 88 a.a.

Antitoxin (RNA)

Gene name	IsrA
Locus tag	-
Coordinates	2927435..2927845 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
P4B13_RS13895	2925042..2925506	+	465	WP_223227916.1	hypothetical protein	-
P4B13_RS13900	2925643..2926947	+	1305	Protein_2700	RHS repeat-associated core domain-containing protein	-
P4B13_RS13905	2926944..2927378	+	435	WP_000789494.1	hypothetical protein	-
P4B13_RS13910	2927425..2927688	-	264	WP_000994215.1	hypothetical protein	Toxin
-	2927435..2927845	+	411	-	-	Antitoxin
P4B13_RS13915	2927930..2928067	+	138	WP_231391191.1	hypothetical protein	-
P4B13_RS13920	2928058..2928366	+	309	WP_166427842.1	hypothetical protein	-
P4B13_RS13925	2928359..2928826	+	468	WP_001284951.1	Imm42 family immunity protein	-
P4B13_RS13930	2928891..2929064	-	174	WP_001531381.1	hypothetical protein	-
P4B13_RS13935	2929117..2929818	+	702	Protein_2707	integrase core domain-containing protein	-
P4B13_RS13940	2930613..2931107	+	495	WP_187789901.1	hypothetical protein	-
P4B13_RS13945	2931240..2931737	+	498	WP_107919743.1	Saf-pilin pilus formation protein SafA	-
P4B13_RS13950	2931812..2932552	+	741	WP_017465813.1	pili assembly chaperone SafB	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	2897742..2940365	42623
	-	flank	IS/Tn	-	-	2929540..2929818	278

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 88 a.a.
• Molecular weight: 9458.71 Da
• Isoelectric Point: 6.4458

>T275338 WP_000994215.1 NZ_CP120671:c2927688-2927425 [Salmonella enterica]
MNASGASVRHINSETCMTTCYSQIPSGDCQEEAGFETGASVVVKISERGLILIAETDEVRDLRKELYQVKKSMKHIKAGV
NNVVNGN

Nucleotide

• Length: 264 bp

Antitoxin

Nucleotide

• Length: 411 bp

>AT275338 NZ_CP120671:2927435-2927845 [Salmonella enterica]
TTCACCACATTATTTACCCCCGCCTTAATATGCTTCATCGACTTTTTCACCTGATAAAGCTCCTTCCGTAGATCCCTCAC
TTCATCCGTTTCTGCAATCAGGATCAAACCCCGCTCGGAGATCTTCACAACAACGCTCGCCCCGGTCTCAAATCCCGCTT
CTTCCTGGCAGTCGCCGCTGGGGATTTGTGAGTAACAGGTGGTCATGCAGGTTTCGCTGTTGATGTGGCGGACGCTGGCG
CCGGAGGCATTCATATTTGCTGACTAAATAAATTCTTAATTCTCCGCCGGATGCTGGCTGATTGTGGAGCTCAGGGTGAG
CGAGTATGGGCGCGACATCCTGGCACTGAGCCCCCCTCTCCCCGGCCAGCTCCGGGCGGTGATGAGCAACCGGCTGCCGG
GGCCGTATTTT

Structures

Antitoxin