Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | yefM-yoeB (relBE)/YoeB-RelB |
Location | 2075307..2075820 | Replicon | chromosome |
Accession | NZ_CP119576 | ||
Organism | Streptococcus agalactiae strain Guangzhou-SAG092 |
Toxin (Protein)
Gene name | yoeB | Uniprot ID | Q8DX49 |
Locus tag | P1I87_RS10610 | Protein ID | WP_000481712.1 |
Coordinates | 2075307..2075561 (-) | Length | 85 a.a. |
Antitoxin (Protein)
Gene name | yefM | Uniprot ID | Q8DX48 |
Locus tag | P1I87_RS10615 | Protein ID | WP_000387490.1 |
Coordinates | 2075554..2075820 (-) | Length | 89 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
P1I87_RS10595 (P1I87_10595) | 2073593..2074003 | - | 411 | WP_000390747.1 | conjugal transfer protein | - |
P1I87_RS10600 (P1I87_10600) | 2074014..2074280 | - | 267 | WP_001055037.1 | hypothetical protein | - |
P1I87_RS10605 (P1I87_10605) | 2074301..2075254 | - | 954 | WP_000565540.1 | conjugal transfer protein | - |
P1I87_RS10610 (P1I87_10610) | 2075307..2075561 | - | 255 | WP_000481712.1 | Txe/YoeB family addiction module toxin | Toxin |
P1I87_RS10615 (P1I87_10615) | 2075554..2075820 | - | 267 | WP_000387490.1 | type II toxin-antitoxin system prevent-host-death family antitoxin | Antitoxin |
P1I87_RS10620 (P1I87_10620) | 2075965..2076438 | - | 474 | WP_000560386.1 | hypothetical protein | - |
P1I87_RS10625 (P1I87_10625) | 2076446..2076928 | - | 483 | WP_000383283.1 | antirestriction protein ArdA | - |
P1I87_RS10630 (P1I87_10630) | 2076981..2077253 | - | 273 | WP_000017154.1 | hypothetical protein | - |
P1I87_RS10635 (P1I87_10635) | 2077388..2077693 | - | 306 | WP_000350427.1 | hypothetical protein | - |
P1I87_RS10640 (P1I87_10640) | 2077960..2079309 | - | 1350 | WP_000491712.1 | AAA family ATPase | - |
P1I87_RS10645 (P1I87_10645) | 2079506..2079805 | - | 300 | WP_000737133.1 | helix-turn-helix transcriptional regulator | - |
P1I87_RS10650 (P1I87_10650) | 2079789..2080166 | - | 378 | WP_000287186.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Integrative and Conjugative Element | - | - | 2062565..2102865 | 40300 | |
flank | IS/Tn | - | - | 2072527..2072916 | 389 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A829IC12 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A829I9V6 |