Detailed information of TA system TA273203

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): IasE-IsrA/-
• Location: 3598756..3599158
• Replicon: chromosome
• Accession: NZ_CP118542
• Organism: Salmonella sp. CVCC 1806

Toxin (Protein)

• Gene name: IasE
• Uniprot ID: -
• Locus tag: PWA52_RS17640
• Protein ID: WP_023209683.1
• Coordinates: 3599030..3599158 (+)
• Length: 43 a.a.

Antitoxin (RNA)

Gene name	IsrA
Locus tag	-
Coordinates	3598756..3599108 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PWA52_RS17605	3594158..3594655	-	498	WP_001030293.1	hypothetical protein	-
PWA52_RS17610	3595277..3595981	-	705	Protein_3455	integrase core domain-containing protein	-
PWA52_RS17615	3596034..3596282	+	249	WP_001746936.1	SymE family type I addiction module toxin	-
PWA52_RS17620	3596414..3596692	-	279	WP_077677834.1	hypothetical protein	-
PWA52_RS17625	3597078..3597476	-	399	WP_000828171.1	hypothetical protein	-
PWA52_RS17630	3598146..3598310	-	165	WP_001746938.1	hypothetical protein	-
PWA52_RS17635	3598346..3598579	-	234	WP_124084119.1	hypothetical protein	-
-	3598756..3599108	-	353	-	-	Antitoxin
PWA52_RS17640	3599030..3599158	+	129	WP_023209683.1	hypothetical protein	Toxin
PWA52_RS17645	3599241..3599561	-	321	WP_223201872.1	Imm8 family immunity protein	-
PWA52_RS17650	3600341..3600706	-	366	WP_000517964.1	hypothetical protein	-
PWA52_RS17655	3600672..3603472	-	2801	Protein_3464	RHS repeat-associated core domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	3589088..3624313	35225
	-	flank	IS/Tn	-	-	3595277..3595558	281
	-	inside	Genomic island	-	-	3586269..3623286	37017

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 43 a.a.
• Molecular weight: 4492.16 Da
• Isoelectric Point: 4.4551

>T273203 WP_023209683.1 NZ_CP118542:3599030-3599158 [Salmonella sp. CVCC 1806]
VKISDGCIVLMADGNEVQELREQLYQAKRVVKGGEGCAGLVD

Nucleotide

• Length: 129 bp

Antitoxin

Nucleotide

• Length: 353 bp

>AT273203 NZ_CP118542:c3599108-3598756 [Salmonella sp. CVCC 1806]
CCTGATAAAGCTGTTCGCGCAGCTCCTGCACCTCGTTACCGTCCGCCATTAGCACAATACACCCGTCCGAAATCTTCACC
GTCACGCCGCTCCCCGGTCTCAAATCCCGCTTCTTCCTGGCAGTCGCCGCCGGGGATTTGTGAGTAACAGGTGGTCATGC
AGGTTTCGCTGTTGATGTGGCGGACGCTGGCGCCGGAGGTATTCATATTTGCTGACTAAATAAATTCTTAATTCTCCGCC
GGATGCTGGCTGATTGTGGAGCTCAGGGTGAGTGAGTATGGGCGCGACATCCTGGCACCGCGCCCCCCTCTCCCCGGCCA
GTGATGAGCAACCGGCTACCGGGGCCGTATTTT

Structures

Antitoxin