Detailed information of TA system TA271047

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): IasE-IsrA/SymE(toxin)
• Location: 3685213..3685627
• Replicon: chromosome
• Accession: NZ_CP117388
• Organism: Salmonella enterica subsp. enterica serovar Uganda strain RM010

Toxin (Protein)

• Gene name: IasE
• Uniprot ID: -
• Locus tag: PQQ04_RS18235
• Protein ID: WP_079798500.1
• Coordinates: 3685370..3685627 (+)
• Length: 86 a.a.

Antitoxin (RNA)

Gene name	IsrA
Locus tag	-
Coordinates	3685213..3685545 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PQQ04_RS18205	3681442..3682179	-	738	WP_001750707.1	pili assembly chaperone SafB	-
PQQ04_RS18210	3682256..3682753	-	498	WP_001750706.1	Saf-pilin pilus formation protein SafA	-
PQQ04_RS18215	3683514..3684218	-	705	Protein_3563	integrase core domain-containing protein	-
PQQ04_RS18220	3684271..3684519	+	249	WP_001738030.1	SymE family type I addiction module toxin	-
PQQ04_RS18225	3684651..3684929	-	279	WP_079798501.1	hypothetical protein	-
PQQ04_RS18230	3685012..3685128	-	117	WP_227457392.1	hypothetical protein	-
-	3685213..3685545	-	333	-	-	Antitoxin
PQQ04_RS18235	3685370..3685627	+	258	WP_079798500.1	SymE family type I addiction module toxin	Toxin
PQQ04_RS18240	3685718..3686095	-	378	WP_000739707.1	Imm8 family immunity protein	-
PQQ04_RS18245	3686828..3687193	-	366	WP_001231281.1	hypothetical protein	-
PQQ04_RS18250	3687159..3688505	-	1347	Protein_3570	RHS repeat-associated core domain-containing protein	-
PQQ04_RS18255	3688567..3688824	+	258	WP_000994229.1	SymE family type I addiction module toxin	-
PQQ04_RS18260	3688888..3689226	-	339	WP_000382983.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	3665026..3694367	29341
	-	flank	IS/Tn	-	-	3683514..3683795	281

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin SymE-like (14-56)

Sequences

Toxin

Protein

• Length: 86 a.a.
• Molecular weight: 9547.82 Da
• Isoelectric Point: 5.0770

>T271047 WP_079798500.1 NZ_CP117388:3685370-3685627 [Salmonella enterica subsp. enterica serovar Uganda]
MNASGVSVRHINSETCMSACYSQIPSQHLKGDWQEEAGFETGRSITVKISQECIVLMADSNEEQKLREQLYKAEQVVKGM
RDVIV

Nucleotide

• Length: 258 bp

Antitoxin

Nucleotide

• Length: 333 bp

>AT271047 NZ_CP117388:c3685545-3685213 [Salmonella enterica subsp. enterica serovar Uganda]
TCCGCCATCAGCACAATACACTCCTGTGAAATCTTCACGGTGATGCTGCGCCCGGTCTCAAATCCCGCTTCTTCCTGCCA
GTCACCCTTAAGGTGCTGGCTGGGGATTTGTGAGTAACAGGCGGACATGCAGGTTTCGCTGTTGATATGGCGGACGCTGA
CGCCGGAGGCATTCATATTTGCTGACTAAATAAATTCTTATTTATCCGCCGGATGCTGGCTGATTGTGGAGCTCAGGGTG
AGTGAGTATGGGCGCGACATCCTGGCACCGCGCCTCCCTCTCCCCGGCCAGCCCCGGCCGGTGATGAGCAGCCGGCTGCC
GGGGCCGTATTTT

Structures

Antitoxin