Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | yjhX-yjhQ/YjhX-GNAT |
Location | 4283556..4284370 | Replicon | chromosome |
Accession | NZ_CP117049 | ||
Organism | Escherichia coli strain MLI106K2 |
Toxin (Protein)
Gene name | yjhX | Uniprot ID | S1PA82 |
Locus tag | NL423_RS21835 | Protein ID | WP_001054376.1 |
Coordinates | 4283556..4283813 (+) | Length | 86 a.a. |
Antitoxin (Protein)
Gene name | yjhQ | Uniprot ID | U9Z4B8 |
Locus tag | NL423_RS21840 | Protein ID | WP_001309181.1 |
Coordinates | 4283825..4284370 (+) | Length | 182 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
NL423_RS21810 (4278816) | 4278816..4279796 | + | 981 | WP_000991438.1 | 9-O-acetyl-N-acetylneuraminic acid deacetylase | - |
NL423_RS21815 (4279906) | 4279906..4280111 | + | 206 | Protein_4050 | HNH endonuclease | - |
NL423_RS21820 (4280411) | 4280411..4281391 | - | 981 | WP_000019400.1 | IS5-like element IS5 family transposase | - |
NL423_RS21825 (4281578) | 4281578..4282818 | - | 1241 | Protein_4052 | helicase YjhR | - |
NL423_RS21830 (4282934) | 4282934..4283065 | + | 132 | WP_001309182.1 | hypothetical protein | - |
NL423_RS21835 (4283556) | 4283556..4283813 | + | 258 | WP_001054376.1 | YjhX family toxin | Toxin |
NL423_RS21840 (4283825) | 4283825..4284370 | + | 546 | WP_001309181.1 | N-acetyltransferase | Antitoxin |
NL423_RS21845 (4284426) | 4284426..4285172 | + | 747 | WP_000354251.1 | class I SAM-dependent methyltransferase | - |
NL423_RS21850 (4285341) | 4285341..4285559 | + | 219 | Protein_4057 | hypothetical protein | - |
NL423_RS21855 (4285597) | 4285597..4285713 | + | 117 | Protein_4058 | VOC family protein | - |
NL423_RS21860 (4285958) | 4285958..4287079 | + | 1122 | WP_000010829.1 | M42 family metallopeptidase | - |
NL423_RS21865 (4287076) | 4287076..4287354 | + | 279 | WP_000722973.1 | PTS sugar transporter subunit IIB SgcB | - |
NL423_RS21870 (4287366) | 4287366..4288679 | + | 1314 | WP_000460843.1 | PTS sugar transporter subunit IIC SgcC | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Genomic island | - | fimI / fimA / fimE / fimB | 4272143..4292594 | 20451 | |
flank | IS/Tn | - | - | 4280411..4281391 | 980 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 86 a.a. Molecular weight: 9734.29 Da Isoelectric Point: 11.0090
>T269941 WP_001054376.1 NZ_CP117049:4283556-4283813 [Escherichia coli]
MNLSRQEQHTLHVLAKGRRIAHVRDSSGRVTSVECYSREGLLLTDCTLAVFKKLKTKKLIKSVNGQPYRINTTELNKVRA
QLDNR
MNLSRQEQHTLHVLAKGRRIAHVRDSSGRVTSVECYSREGLLLTDCTLAVFKKLKTKKLIKSVNGQPYRINTTELNKVRA
QLDNR
Download Length: 258 bp
Antitoxin
Download Length: 182 a.a. Molecular weight: 19956.90 Da Isoelectric Point: 6.3277
>AT269941 WP_001309181.1 NZ_CP117049:4283825-4284370 [Escherichia coli]
MTVHHFTFHITDKSDASDIREVETRAFGFSKEADLVASLLEDESARPALSLLARYEGKAVGHILFTRATFKGEMDSPLMH
ILAPLAVIPEYQGMGVGGRLIRTGIEHLRLMGCQTVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEEHKACWMMQSLTA
QPMTLTGHIRCADPDETGALT
MTVHHFTFHITDKSDASDIREVETRAFGFSKEADLVASLLEDESARPALSLLARYEGKAVGHILFTRATFKGEMDSPLMH
ILAPLAVIPEYQGMGVGGRLIRTGIEHLRLMGCQTVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEEHKACWMMQSLTA
QPMTLTGHIRCADPDETGALT
Download Length: 546 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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