Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1910376..1910558 Replicon chromosome
Accession NC_017347
Organism Staphylococcus aureus subsp. aureus T0131

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag SAT0131_RS15790 Protein ID WP_001801861.1
Coordinates 1910376..1910471 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1910499..1910558 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SAT0131_RS09395 1906036..1906662 + 627 WP_000669049.1 hypothetical protein -
SAT0131_RS09400 1906703..1907047 + 345 WP_000627551.1 DUF3969 family protein -
SAT0131_RS09405 1907145..1907696 + 552 WP_000414205.1 hypothetical protein -
SAT0131_RS09410 1907914..1908555 - 642 WP_000494956.1 ImmA/IrrE family metallo-endopeptidase -
SAT0131_RS09415 1908669..1908854 - 186 WP_000809857.1 hypothetical protein -
SAT0131_RS09420 1908856..1909032 - 177 WP_000375476.1 hypothetical protein -
SAT0131_RS09425 1909043..1909426 - 384 WP_000070811.1 hypothetical protein -
SAT0131_RS09435 1910030..1910173 - 144 WP_001549059.1 transposase -
SAT0131_RS15790 1910376..1910471 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1910499..1910558 - 60 - - Antitoxin
SAT0131_RS09440 1910594..1910695 + 102 WP_001791893.1 hypothetical protein -
SAT0131_RS15370 1910673..1910849 - 177 Protein_1822 transposase -
SAT0131_RS09445 1911043..1911420 - 378 WP_001037045.1 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA 1903476..1940652 37176


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T26699 WP_001801861.1 NC_017347:1910376-1910471 [Staphylococcus aureus subsp. aureus T0131]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T26699 NC_017347:1910376-1910471 [Staphylococcus aureus subsp. aureus T0131]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 60 bp

>AT26699 NC_017347:c1910558-1910499 [Staphylococcus aureus subsp. aureus T0131]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References