265938

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 1008220..1009034 Replicon chromosome
Accession NZ_CP113537
Organism Salmonella enterica strain YZY

Toxin (Protein)


Gene name TacT3 Uniprot ID -
Locus tag OXV04_RS04820 Protein ID WP_126523877.1
Coordinates 1008220..1008747 (-) Length 176 a.a.

Antitoxin (Protein)


Gene name TacA3 Uniprot ID M7S6I2
Locus tag OXV04_RS04825 Protein ID WP_000855694.1
Coordinates 1008744..1009034 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OXV04_RS04800 (1003520) 1003520..1006087 - 2568 WP_001005802.1 DNA mismatch repair protein MutS -
OXV04_RS04805 (1006246) 1006246..1006767 + 522 WP_061383865.1 hypothetical protein -
OXV04_RS04810 (1006939) 1006939..1007595 - 657 WP_058821376.1 protein-serine/threonine phosphatase -
OXV04_RS04815 (1007930) 1007930..1008147 + 218 Protein_944 IS5/IS1182 family transposase -
OXV04_RS04820 (1008220) 1008220..1008747 - 528 WP_126523877.1 GNAT family N-acetyltransferase Toxin
OXV04_RS04825 (1008744) 1008744..1009034 - 291 WP_000855694.1 DUF1778 domain-containing protein Antitoxin
OXV04_RS04830 (1009304) 1009304..1009489 - 186 Protein_947 IS3 family transposase -
OXV04_RS04835 (1009744) 1009744..1010070 + 327 WP_000393302.1 hypothetical protein -
OXV04_RS04840 (1010343) 1010343..1010690 - 348 WP_001669174.1 DUF1493 family protein -
OXV04_RS04845 (1010675) 1010675..1011124 - 450 WP_023261375.1 hypothetical protein -
OXV04_RS04850 (1011555) 1011555..1011998 - 444 WP_126523878.1 SPI-1 type III secretion system invasion lipoprotein InvH -
OXV04_RS04855 (1012455) 1012455..1013105 + 651 WP_001674874.1 type III secretion system transcriptional activator InvF -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Genomic island - invH / invF / invG / invE / invA / invB 1006939..1018418 11479
- flank IS/Tn - - 1008007..1008147 140


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(1-95)


Sequences

Toxin        


Download         Length: 176 a.a.        Molecular weight: 19097.96 Da        Isoelectric Point: 9.6420

>T265938 WP_126523877.1 NZ_CP113537:c1008747-1008220 [Salmonella enterica]
MMFTDWHEAAIGKTHNRMNFDCGDADLNQFLQRHVRQNHEKGTTKTYVALDNSDVTRIHGFYSVSPASLIYAQVPGAISK
GLGRYDVPVFRLGRLAVDKSMQGQGLGAQLLLSAGKRCIQAALQVGGVALLIDAKNKQVCDWYKGFGAVPLNDQPLSLLL
SFKTLYAALSASGRL

Download         Length: 528 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10664.50 Da        Isoelectric Point: 6.3133

>AT265938 WP_000855694.1 NZ_CP113537:c1009034-1008744 [Salmonella enterica]
MKTMPQIAIESNERLSLRVSTDAKKLIVRAAAIQQTNLTDFVVSNVLPVAQKIVDAAERVYLTERDTQMIMEILDNPPAP
NEKLLAAAFALPDMKK

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A3V8SJE7

References