Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) IasE-IsrA/SymE(toxin)
Location 3589636..3589842 Replicon chromosome
Accession NZ_CP113364
Organism Salmonella enterica subsp. enterica strain KNP01

Toxin (Protein)


Gene name IasE Uniprot ID A0A3Y1TUH5
Locus tag OU685_RS17655 Protein ID WP_026080916.1
Coordinates 3589636..3589842 (+) Length 69 a.a.

Antitoxin (RNA)


Gene name IsrA
Locus tag -
Coordinates 3589647..3589832 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OU685_RS17620 3584781..3585008 + 228 WP_017442171.1 SymE family type I addiction module toxin -
OU685_RS17625 3585061..3585543 - 483 WP_017442170.1 immunity 26/phosphotriesterase HocA family protein -
OU685_RS17630 3586062..3586508 - 447 WP_000935097.1 protein SciX -
OU685_RS17635 3586502..3587470 - 969 Protein_3447 polymorphic toxin type 47 domain-containing protein -
OU685_RS17640 3587896..3588030 + 135 Protein_3448 SymE family type I addiction module toxin -
OU685_RS17645 3588099..3588386 - 288 WP_017442165.1 hypothetical protein -
OU685_RS17650 3588389..3589642 - 1254 Protein_3450 RHS domain-containing protein -
OU685_RS17655 3589636..3589842 + 207 WP_026080916.1 SymE family type I addiction module toxin Toxin
- 3589647..3589832 - 186 - - Antitoxin
OU685_RS17660 3589889..3590167 - 279 WP_017442162.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3568002..3612372 44370


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SymE-like

(1-34)


Sequences

Toxin        


Download         Length: 69 a.a.        Molecular weight: 7592.80 Da        Isoelectric Point: 6.4569

>T265695 WP_026080916.1 NZ_CP113364:3589636-3589842 [Salmonella enterica subsp. enterica]
IPELHLKGDWLAEAGFETGTSVTVKISEGCLILIAETDEVRDLRKELYLVKKSMKHIKAGVNNVVNRD

Download         Length: 207 bp

Antitoxin


Download         Length: 186 bp

>AT265695 NZ_CP113364:c3589832-3589647 [Salmonella enterica subsp. enterica]
TTCACCACATTATTTACCCCCGCCTTAATATGCTTCATCGACTTTTTCACCAGATAAAGCTCCTTCCGTAGATCCCTCAC
TTCGTCCGTCTCTGCAATCAGGATCAAACACCCCTCCGAGATCTTCACGGTTACGCTCGTCCCGGTCTCAAATCCCGCCT
CGGCCAGCCAGTCGCCCTTAAGATGC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3Y1TUH5

Antitoxin

Download structure file

References