Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1952846..1953028 Replicon chromosome
Accession NC_017331
Organism Staphylococcus aureus subsp. aureus TW20

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag SATW20_RS16795 Protein ID WP_001801861.1
Coordinates 1952846..1952941 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1952969..1953028 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SATW20_RS09665 1948506..1949132 + 627 WP_000669046.1 hypothetical protein -
SATW20_RS09670 1949173..1949517 + 345 WP_000627551.1 DUF3969 family protein -
SATW20_RS09675 1949615..1950166 + 552 WP_000414205.1 hypothetical protein -
SATW20_RS09680 1950384..1951025 - 642 WP_000494956.1 ImmA/IrrE family metallo-endopeptidase -
SATW20_RS09685 1951139..1951324 - 186 WP_000809857.1 hypothetical protein -
SATW20_RS09690 1951326..1951502 - 177 WP_000375476.1 hypothetical protein -
SATW20_RS09695 1951513..1951896 - 384 WP_000070811.1 hypothetical protein -
SATW20_RS09705 1952500..1952643 - 144 WP_001549059.1 transposase -
SATW20_RS16795 1952846..1952941 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1952969..1953028 - 60 - - Antitoxin
SATW20_RS09710 1953064..1953165 + 102 WP_001791893.1 hypothetical protein -
SATW20_RS16355 1953143..1953319 - 177 Protein_1877 transposase -
SATW20_RS09715 1953513..1953890 - 378 WP_001037045.1 DUF1433 domain-containing protein -
SATW20_RS09720 1954411..1955679 - 1269 Protein_1879 ATP-binding protein -
SATW20_RS09730 1955731..1956902 - 1172 Protein_1880 IS256-like element IS256 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA 1945946..1986197 40251


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T26554 WP_001801861.1 NC_017331:1952846-1952941 [Staphylococcus aureus subsp. aureus TW20]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T26554 NC_017331:1952846-1952941 [Staphylococcus aureus subsp. aureus TW20]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 60 bp

>AT26554 NC_017331:c1953028-1952969 [Staphylococcus aureus subsp. aureus TW20]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References