Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/YafQ-RelB |
Location | 1564319..1564885 | Replicon | chromosome |
Accession | NC_017219 | ||
Organism | Bifidobacterium longum subsp. infantis ATCC 15697 = JCM 1222 = DSM |
Toxin (Protein)
Gene name | relE | Uniprot ID | W6EX94 |
Locus tag | BLIJ_RS07270 | Protein ID | WP_003831807.1 |
Coordinates | 1564592..1564885 (+) | Length | 98 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | - |
Locus tag | BLIJ_RS07265 | Protein ID | WP_014484914.1 |
Coordinates | 1564319..1564588 (+) | Length | 90 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
BLIJ_RS07240 | 1560069..1560763 | - | 695 | Protein_1414 | response regulator transcription factor | - |
BLIJ_RS07245 | 1560889..1561404 | + | 516 | WP_013140733.1 | hypothetical protein | - |
BLIJ_RS07250 | 1561401..1562291 | + | 891 | WP_014484913.1 | hypothetical protein | - |
BLIJ_RS07255 | 1562288..1562968 | + | 681 | WP_003829413.1 | ABC transporter ATP-binding protein | - |
BLIJ_RS07260 | 1562965..1564134 | + | 1170 | WP_012577732.1 | ABC transporter permease | - |
BLIJ_RS07265 | 1564319..1564588 | + | 270 | WP_014484914.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
BLIJ_RS07270 | 1564592..1564885 | + | 294 | WP_003831807.1 | type II toxin-antitoxin system YafQ family toxin | Toxin |
BLIJ_RS13665 | 1564943..1565223 | + | 281 | Protein_1421 | hypothetical protein | - |
BLIJ_RS07280 | 1565554..1566105 | + | 552 | WP_012577735.1 | RNA polymerase sigma factor | - |
BLIJ_RS07285 | 1566139..1566966 | + | 828 | WP_012577736.1 | hypothetical protein | - |
BLIJ_RS07290 | 1567098..1567724 | + | 627 | WP_012577737.1 | hypothetical protein | - |
BLIJ_RS07295 | 1567721..1568503 | + | 783 | WP_012577738.1 | hypothetical protein | - |
BLIJ_RS07300 | 1568556..1569431 | + | 876 | WP_003829425.1 | ABC transporter ATP-binding protein | - |
BLIJ_RS07305 | 1569485..1569883 | + | 399 | WP_003829426.1 | superoxide dismutase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
inside | Genomic island | - | - | 1555334..1576692 | 21358 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 98 a.a. Molecular weight: 11218.98 Da Isoelectric Point: 9.7881
>T26378 WP_003831807.1 NC_017219:1564592-1564885 [Bifidobacterium longum subsp. infantis ATCC 15697 = JCM 1222 = DSM]
MLKPDYTAAFQRDIKKLKRKHTDLRPLKEVIRLVLEDTADSKEVLRRRHRAHTLTGDLNGVLECHIGNAGDWLLLWIRDD
GTAMFMRTGSHDELLGK
MLKPDYTAAFQRDIKKLKRKHTDLRPLKEVIRLVLEDTADSKEVLRRRHRAHTLTGDLNGVLECHIGNAGDWLLLWIRDD
GTAMFMRTGSHDELLGK
Download Length: 294 bp
>T26378 NC_017219:1564592-1564885 [Bifidobacterium longum subsp. infantis ATCC 15697 = JCM 1222 = DSM]
ATGCTCAAACCGGATTACACAGCGGCATTCCAGCGAGATATCAAGAAACTCAAACGCAAGCACACTGATTTACGCCCGCT
GAAAGAAGTCATTCGTCTGGTTCTTGAGGACACGGCGGACTCCAAGGAAGTATTGAGGCGTAGGCATCGCGCCCACACAC
TTACCGGTGATTTAAACGGCGTATTGGAATGCCACATCGGCAATGCCGGCGACTGGCTGCTTCTATGGATTCGCGATGAT
GGTACCGCCATGTTCATGCGAACCGGCAGCCATGACGAACTGTTGGGCAAATAG
ATGCTCAAACCGGATTACACAGCGGCATTCCAGCGAGATATCAAGAAACTCAAACGCAAGCACACTGATTTACGCCCGCT
GAAAGAAGTCATTCGTCTGGTTCTTGAGGACACGGCGGACTCCAAGGAAGTATTGAGGCGTAGGCATCGCGCCCACACAC
TTACCGGTGATTTAAACGGCGTATTGGAATGCCACATCGGCAATGCCGGCGACTGGCTGCTTCTATGGATTCGCGATGAT
GGTACCGCCATGTTCATGCGAACCGGCAGCCATGACGAACTGTTGGGCAAATAG
Antitoxin
Download Length: 90 a.a. Molecular weight: 9902.25 Da Isoelectric Point: 4.7872
>AT26378 WP_014484914.1 NC_017219:1564319-1564588 [Bifidobacterium longum subsp. infantis ATCC 15697 = JCM 1222 = DSM]
VSMASVTVRVDADTKQKAANIAEDLGLDLSSVTRAFYKQIVRERRIPLNLSYTTVPPETMEALDEAKNRLADGKPRFNSA
DEMFDSLVI
VSMASVTVRVDADTKQKAANIAEDLGLDLSSVTRAFYKQIVRERRIPLNLSYTTVPPETMEALDEAKNRLADGKPRFNSA
DEMFDSLVI
Download Length: 270 bp
>AT26378 NC_017219:1564319-1564588 [Bifidobacterium longum subsp. infantis ATCC 15697 = JCM 1222 = DSM]
GTGAGCATGGCATCCGTCACAGTCCGCGTGGATGCGGACACCAAGCAGAAAGCCGCAAACATTGCCGAGGATCTCGGTCT
GGACTTGTCTTCGGTCACCCGCGCCTTCTACAAGCAGATTGTCCGGGAGAGGCGCATTCCCCTAAACCTTTCCTATACGA
CCGTGCCGCCTGAAACCATGGAGGCCCTTGACGAGGCGAAGAACAGGCTCGCCGACGGCAAACCTCGTTTCAACAGTGCC
GATGAGATGTTCGATTCGTTGGTAATCTGA
GTGAGCATGGCATCCGTCACAGTCCGCGTGGATGCGGACACCAAGCAGAAAGCCGCAAACATTGCCGAGGATCTCGGTCT
GGACTTGTCTTCGGTCACCCGCGCCTTCTACAAGCAGATTGTCCGGGAGAGGCGCATTCCCCTAAACCTTTCCTATACGA
CCGTGCCGCCTGAAACCATGGAGGCCCTTGACGAGGCGAAGAACAGGCTCGCCGACGGCAAACCTCGTTTCAACAGTGCC
GATGAGATGTTCGATTCGTTGGTAATCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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