Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) CD-RCd/-
Location 1326557..1326762 Replicon chromosome
Accession NC_017173
Organism Clostridium difficile CF5

Toxin (Protein)


Gene name CD1233.1 Uniprot ID A0A069A9H6
Locus tag CDCF5_RS18895 Protein ID WP_009896140.1
Coordinates 1326557..1326709 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name SQ808
Locus tag -
Coordinates 1326689..1326762 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CDCF5_RS06115 1322026..1322310 - 285 WP_003419254.1 sigma-70 family RNA polymerase sigma factor -
CDCF5_RS06120 1322333..1323850 - 1518 WP_003433404.1 recombinase family protein -
CDCF5_RS06125 1323975..1324796 - 822 WP_003433401.1 tetratricopeptide repeat protein -
CDCF5_RS06130 1324987..1326414 + 1428 WP_021387779.1 cell wall-binding protein Cwp26 -
CDCF5_RS18895 1326557..1326709 + 153 WP_009896140.1 hypothetical protein Toxin
- 1326689..1326762 - 74 NuclAT_8 - Antitoxin
CDCF5_RS06135 1327743..1327967 - 225 WP_003433396.1 helix-turn-helix domain-containing protein -
CDCF5_RS06140 1328657..1328812 + 156 WP_003433394.1 hypothetical protein -
CDCF5_RS06145 1329058..1329309 + 252 WP_003419270.1 hypothetical protein -
CDCF5_RS06150 1330529..1330912 - 384 WP_003433385.1 hypothetical protein -
CDCF5_RS06155 1331039..1331383 + 345 WP_003433383.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5811.96 Da        Isoelectric Point: 11.1039

>T26325 WP_009896140.1 NC_017173:1326557-1326709 [Clostridioides difficile CF5]
MDNFLFNVLASLTASVVVYLISKLFKKAKSHSRTKSDLRVEFKFIFKSKK

Download         Length: 153 bp

>T26325 NC_017173:1326557-1326709 [Clostridioides difficile CF5]
ATGGATAACTTTTTGTTTAATGTTTTAGCTAGTTTAACAGCTAGTGTGGTAGTTTACTTAATCAGTAAACTATTCAAAAA
AGCAAAAAGCCACTCTCGCACAAAGAGTGACTTACGAGTTGAATTTAAATTTATATTTAAATCCAAAAAATAA

Antitoxin


Download         Length: 74 bp

>AT26325 NC_017173:c1326762-1326689 [Clostridioides difficile CF5]
AAGAAGAACTACAATCTATTTTGCGTTAGAGTGGAGTTCATCATAAACAGAGTTTATTTTTTGGATTTAAATAT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A069A9H6

Antitoxin

Download structure file

References