Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1790439..1790621 Replicon chromosome
Accession NC_016912
Organism Staphylococcus aureus subsp. aureus VC40

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag SAVC_RS14350 Protein ID WP_001801861.1
Coordinates 1790439..1790534 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1790562..1790621 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SAVC_RS08765 1786099..1786725 + 627 WP_000669046.1 hypothetical protein -
SAVC_RS08770 1786766..1787110 + 345 WP_000627551.1 DUF3969 family protein -
SAVC_RS08775 1787208..1787759 + 552 WP_000414205.1 hypothetical protein -
SAVC_RS08780 1787977..1788618 - 642 WP_000494956.1 ImmA/IrrE family metallo-endopeptidase -
SAVC_RS08785 1788732..1788917 - 186 WP_000809857.1 hypothetical protein -
SAVC_RS08790 1788919..1789095 - 177 WP_000375476.1 hypothetical protein -
SAVC_RS08795 1789106..1789489 - 384 WP_000070812.1 hypothetical protein -
SAVC_RS08805 1790093..1790236 - 144 WP_001549059.1 transposase -
SAVC_RS14350 1790439..1790534 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1790562..1790621 - 60 - - Antitoxin
SAVC_RS08810 1790657..1790758 + 102 WP_001791893.1 hypothetical protein -
SAVC_RS14025 1790736..1790912 - 177 Protein_1687 transposase -
SAVC_RS08815 1791106..1791483 - 378 WP_001037045.1 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA 1783539..1823710 40171


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T26096 WP_001801861.1 NC_016912:1790439-1790534 [Staphylococcus aureus subsp. aureus VC40]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T26096 NC_016912:1790439-1790534 [Staphylococcus aureus subsp. aureus VC40]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 60 bp

>AT26096 NC_016912:c1790621-1790562 [Staphylococcus aureus subsp. aureus VC40]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References