255056

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbDE/ParE-DnaT
Location 19503..20034 Replicon plasmid unnamed
Accession NZ_CP103446
Organism Erwinia pyrifoliae strain CP201486

Toxin (Protein)


Gene name stbE Uniprot ID E3DL65
Locus tag NYP84_RS19385 Protein ID WP_011078058.1
Coordinates 19503..19790 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name stbD Uniprot ID Q7X3U3
Locus tag NYP84_RS19390 Protein ID WP_011078059.1
Coordinates 19780..20034 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NYP84_RS19365 (NYP84_19365) 16003..17559 - 1557 WP_041473953.1 methyl-accepting chemotaxis protein -
NYP84_RS19370 (NYP84_19370) 18067..18480 - 414 WP_011113999.1 helix-turn-helix domain-containing protein -
NYP84_RS19375 (NYP84_19375) 18481..18795 - 315 WP_041473956.1 type II toxin-antitoxin system HigB family toxin -
NYP84_RS19380 (NYP84_19380) 19059..19343 - 285 WP_011078079.1 VF530 family DNA-binding protein -
NYP84_RS19385 (NYP84_19385) 19503..19790 - 288 WP_011078058.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NYP84_RS19390 (NYP84_19390) 19780..20034 - 255 WP_011078059.1 plasmid stabilization protein Antitoxin
NYP84_RS19395 (NYP84_19395) 20245..21210 - 966 WP_011078060.1 ThiF family adenylyltransferase -
NYP84_RS19400 (NYP84_19400) 21226..21984 - 759 WP_012814638.1 thiazole synthase -
NYP84_RS19405 (NYP84_19405) 21988..22185 - 198 WP_012814637.1 sulfur carrier protein ThiS -
NYP84_RS19410 (NYP84_19410) 22182..23114 - 933 WP_041473952.1 FAD-dependent oxidoreductase -
NYP84_RS19415 (NYP84_19415) 23490..23651 - 162 Protein_26 Txe/YoeB family addiction module toxin -
NYP84_RS19420 (NYP84_19420) 23831..24415 + 585 WP_259818180.1 recombinase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Non-Mobilizable plasmid - pla 1..34668 34668
flank IS/Tn - - 23831..24415 584


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-85)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11197.09 Da        Isoelectric Point: 10.6516

>T255056 WP_011078058.1 NZ_CP103446:c19790-19503 [Erwinia pyrifoliae]
MTYKLKFVPSAEKEWKRLGHPVREQFKKKLAERLENPRVPSAQLHGRKDQYKIKLKSAGYRLVYLVQEHTITIMVMGIGK
REGNQIYSDTENRLP

Download         Length: 288 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9210.56 Da        Isoelectric Point: 3.8705

>AT255056 WP_011078059.1 NZ_CP103446:c20034-19780 [Erwinia pyrifoliae]
MAFNILTNTAASITDLKRDPMGTVRAAEGETIAILNRNEPAFYCVPPAMYAYLMELAEDAELGCIVDDRMSELPVAKEIS
LDDL

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB E3DL65

Antitoxin

Source ID Structure
AlphaFold DB Q7X3U3

References