Detailed information of TA system TA251117

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): IasE-IsrA/-
• Location: 3603210..3603630
• Replicon: chromosome
• Accession: NZ_CP100702
• Organism: Salmonella enterica subsp. enterica serovar Thompson strain R18.0872

Toxin (Protein)

• Gene name: IasE
• Uniprot ID: A0A8E7RAJ3
• Locus tag: NL734_RS17845
• Protein ID: WP_000994215.1
• Coordinates: 3603367..3603630 (+)
• Length: 88 a.a.

Antitoxin (RNA)

Gene name	IsrA
Locus tag	-
Coordinates	3603210..3603620 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
NL734_RS17805	3598512..3599252	-	741	WP_017465813.1	pili assembly chaperone SafB	-
NL734_RS17810	3599327..3599824	-	498	WP_107919743.1	Saf-pilin pilus formation protein SafA	-
NL734_RS17815	3599957..3600451	-	495	WP_017465815.1	hypothetical protein	-
NL734_RS17820	3601237..3601938	-	702	Protein_3484	integrase core domain-containing protein	-
NL734_RS17825	3601991..3602164	+	174	WP_001531381.1	hypothetical protein	-
NL734_RS17830	3602229..3602696	-	468	WP_001284951.1	Imm42 family immunity protein	-
NL734_RS17835	3602689..3602997	-	309	WP_166427842.1	hypothetical protein	-
NL734_RS17840	3602988..3603125	-	138	WP_231391191.1	hypothetical protein	-
-	3603210..3603620	-	411	-	-	Antitoxin
NL734_RS17845	3603367..3603630	+	264	WP_000994215.1	hypothetical protein	Toxin
NL734_RS17850	3603677..3604111	-	435	WP_000789494.1	hypothetical protein	-
NL734_RS17855	3604108..3605412	-	1305	Protein_3491	RHS domain-containing protein	-
NL734_RS17860	3605549..3606013	-	465	WP_223227916.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	3591437..3634801	43364

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 88 a.a.
• Molecular weight: 9458.71 Da
• Isoelectric Point: 6.4458

>T251117 WP_000994215.1 NZ_CP100702:3603367-3603630 [Salmonella enterica subsp. enterica serovar Thompson]
MNASGASVRHINSETCMTTCYSQIPSGDCQEEAGFETGASVVVKISERGLILIAETDEVRDLRKELYQVKKSMKHIKAGV
NNVVNGN

Nucleotide

• Length: 264 bp

Antitoxin

Nucleotide

• Length: 411 bp

>AT251117 NZ_CP100702:c3603620-3603210 [Salmonella enterica subsp. enterica serovar Thompson]
TTCACCACATTATTTACCCCCGCCTTAATATGCTTCATCGACTTTTTCACCTGATAAAGCTCCTTCCGTAGATCCCTCAC
TTCATCCGTTTCTGCAATCAGGATCAAACCCCGCTCGGAGATCTTCACAACAACGCTCGCCCCGGTCTCAAATCCCGCTT
CTTCCTGGCAGTCGCCGCTGGGGATTTGTGAGTAACAGGTGGTCATGCAGGTTTCGCTGTTGATGTGGCGGACGCTGGCG
CCGGAGGCATTCATATTTGCTGACTAAATAAATTCTTAATTCTCCGCCGGATGCTGGCTGATTGTGGAGCTCAGGGTGAG
CGAGTATGGGCGCGACATCCTGGCACTGAGCCCCCCTCTCCCCGGCCAGCTCCGGGCGGTGATGAGCAACCGGCTGCCGG
GGCCGTATTTT

Structures

Antitoxin