Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/ParE-RelB |
| Location | 2223047..2223573 | Replicon | chromosome |
| Accession | NZ_CP099588 | ||
| Organism | Escherichia coli strain EMG2 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | S1EXL1 |
| Locus tag | NHF38_RS10725 | Protein ID | WP_000323025.1 |
| Coordinates | 2223286..2223573 (+) | Length | 96 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | S1F6D3 |
| Locus tag | NHF38_RS10720 | Protein ID | WP_000534858.1 |
| Coordinates | 2223047..2223286 (+) | Length | 80 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NHF38_RS10665 (2218074) | 2218074..2218841 | - | 768 | Protein_2095 | exonuclease | - |
| NHF38_RS10670 (2218934) | 2218934..2219125 | - | 192 | WP_001083297.1 | lysis protein YdfD | - |
| NHF38_RS10675 (2219122) | 2219122..2219310 | - | 189 | WP_000854559.1 | cell division inhibition protein DicB | - |
| NHF38_RS10680 (2219878) | 2219878..2220096 | - | 219 | WP_001171942.1 | protein YdfC | - |
| NHF38_RS23305 (2220126) | 2220126..2220254 | - | 129 | WP_000344964.1 | protein YdfB | - |
| NHF38_RS10685 (2220256) | 2220256..2220411 | - | 156 | WP_000379575.1 | DUF1391 family protein | - |
| NHF38_RS10690 (2220578) | 2220578..2220985 | - | 408 | WP_000448564.1 | DNA-binding transcriptional dual regulator DicA | - |
| NHF38_RS10695 (2221069) | 2221069..2221299 | + | 231 | WP_000920568.1 | dicB transcriptional regulator DicC | - |
| NHF38_RS10700 (2221283) | 2221283..2221561 | + | 279 | Protein_2103 | protein YdfX | - |
| NHF38_RS10705 (2221596) | 2221596..2221745 | + | 150 | WP_011443592.1 | protein YdfW | - |
| NHF38_RS10710 (2222182) | 2222182..2222514 | - | 333 | WP_001301033.1 | FlxA-like family protein | - |
| NHF38_RS10715 (2222717) | 2222717..2223022 | - | 306 | WP_001326990.1 | protein YdfV | - |
| NHF38_RS10720 (2223047) | 2223047..2223286 | + | 240 | WP_000534858.1 | type II toxin-antitoxin system antitoxin RelB | Antitoxin |
| NHF38_RS10725 (2223286) | 2223286..2223573 | + | 288 | WP_000323025.1 | type II toxin-antitoxin system mRNA interferase RelE | Toxin |
| NHF38_RS10730 (2223645) | 2223645..2223800 | + | 156 | WP_000813254.1 | type I toxin-antitoxin system toxin HokD | - |
| NHF38_RS10735 (2224017) | 2224017..2224268 | + | 252 | WP_000980994.1 | protein Rem | - |
| NHF38_RS10740 (2224335) | 2224335..2224613 | + | 279 | WP_012304870.1 | hypothetical protein | - |
| NHF38_RS10745 (2224615) | 2224615..2225664 | + | 1050 | WP_001393597.1 | DUF968 domain-containing protein | - |
| NHF38_RS10750 (2225678) | 2225678..2226430 | + | 753 | WP_001047135.1 | antitermination protein | - |
| NHF38_RS10755 (2226708) | 2226708..2226797 | - | 90 | WP_120795389.1 | hypothetical protein | - |
| NHF38_RS10760 (2226852) | 2226852..2227064 | - | 213 | WP_000087756.1 | cold shock-like protein CspF | - |
| NHF38_RS10765 (2227365) | 2227365..2227580 | + | 216 | WP_000066484.1 | cold shock-like protein CspB | - |
| NHF38_RS10770 (2227944) | 2227944..2228114 | - | 171 | WP_211180497.1 | putative zinc-binding protein YnfU | - |
| NHF38_RS10775 (2228334) | 2228334..2228549 | + | 216 | WP_000839590.1 | phage lysis protein EssD | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| inside | Prophage | - | - | 2216211..2239704 | 23493 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|