Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | ralRA/- |
Location | 1398724..1399095 | Replicon | chromosome |
Accession | NC_012971 | ||
Organism | Escherichia coli BL21(DE3) |
Toxin (Protein)
Gene name | ralR | Uniprot ID | F4VC37 |
Locus tag | ECD_RS07095 | Protein ID | WP_001317028.1 |
Coordinates | 1398901..1399095 (-) | Length | 65 a.a. |
Antitoxin (RNA)
Gene name | ralA | ||
Locus tag | - | ||
Coordinates | 1398724..1398902 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
ECD_RS07070 | 1394679..1396052 | + | 1374 | WP_000123737.1 | ATP-dependent RNA helicase DbpA | - |
ECD_RS07075 | 1396181..1397116 | - | 936 | WP_001157407.1 | tRNA 2-thiocytidine(32) synthetase TtcA | - |
ECD_RS23305 | 1397168..1398403 | - | 1236 | WP_000040858.1 | site-specific integrase | - |
ECD_RS07085 | 1398405..1398620 | - | 216 | WP_000079604.1 | excisionase XisR | - |
ECD_RS07090 | 1398699..1398908 | - | 210 | WP_000276809.1 | double-strand break reduction protein RcbA | - |
- | 1398724..1398902 | + | 179 | NuclAT_0 | - | Antitoxin |
- | 1398724..1398902 | + | 179 | NuclAT_0 | - | Antitoxin |
- | 1398724..1398902 | + | 179 | NuclAT_0 | - | Antitoxin |
- | 1398724..1398902 | + | 179 | NuclAT_0 | - | Antitoxin |
ECD_RS07095 | 1398901..1399095 | - | 195 | WP_001317028.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | Toxin |
ECD_RS07100 | 1399152..1399961 | - | 810 | WP_000166319.1 | recombination protein RecT | - |
ECD_RS07105 | 1399954..1401053 | - | 1100 | Protein_1349 | PD-(D/E)XK nuclease-like domain-containing protein | - |
ECD_RS07110 | 1401155..1401430 | - | 276 | WP_000632297.1 | protein RacC | - |
ECD_RS07115 | 1401505..1401675 | - | 171 | WP_001352098.1 | conserved protein, Rac prophage | - |
ECD_RS07120 | 1401675..1401896 | - | 222 | WP_000560223.1 | killing protein KilR | - |
ECD_RS07125 | 1402338..1402826 | + | 489 | WP_001312793.1 | superinfection exclusion protein B | - |
ECD_RS22665 | 1402823..1402978 | - | 156 | WP_001169151.1 | YdaF family protein | - |
ECD_RS07130 | 1403122..1403334 | + | 213 | WP_012775985.1 | phage lysis protein EssD | - |
ECD_RS07135 | 1403339..1403683 | + | 345 | WP_000193293.1 | YdfR family protein | - |
ECD_RS07140 | 1403649..1403921 | - | 273 | WP_000370546.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
inside | Prophage | - | - | 1397168..1409233 | 12065 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 65 a.a. Molecular weight: 7018.89 Da Isoelectric Point: 8.9538
>T24145 WP_001317028.1 NC_012971:c1399095-1398901 [Escherichia coli BL21(DE3)]
MRYDNVKPCPFCGCPSVTVKAISGYYRAKCNGCESRTGYGGSEKEALERWNKRTTGNNNGGVHV
MRYDNVKPCPFCGCPSVTVKAISGYYRAKCNGCESRTGYGGSEKEALERWNKRTTGNNNGGVHV
Download Length: 195 bp
>T24145 NC_012971:c1399095-1398901 [Escherichia coli BL21(DE3)]
ATGAGATATGACAATGTTAAACCATGTCCATTTTGTGGTTGTCCATCAGTAACGGTGAAAGCCATTTCAGGATATTACCG
AGCGAAGTGTAACGGATGCGAATCCCGAACCGGTTATGGTGGAAGTGAAAAAGAAGCACTCGAAAGATGGAATAAACGAA
CCACTGGAAATAATAATGGAGGTGTTCATGTATAA
ATGAGATATGACAATGTTAAACCATGTCCATTTTGTGGTTGTCCATCAGTAACGGTGAAAGCCATTTCAGGATATTACCG
AGCGAAGTGTAACGGATGCGAATCCCGAACCGGTTATGGTGGAAGTGAAAAAGAAGCACTCGAAAGATGGAATAAACGAA
CCACTGGAAATAATAATGGAGGTGTTCATGTATAA
Antitoxin
Download Length: 179 bp
>AT24145 NC_012971:1398724-1398902 [Escherichia coli BL21(DE3)]
GAGGACTGAAGTTTCTCGCAATTAAAATTTATCAGTTTTACTTTCTGCTCTCTGGAAACGCCTGCTTCTTTTTTACCTGA
GAGCATTTTTTCGCATTCTGATTTCGTTAGTTTAGATTTTGAATATCTTGTCCAGTTAGTAGGAGTGCCACCTTCCTTTT
CAATAGTGGCGGTAATTTT
GAGGACTGAAGTTTCTCGCAATTAAAATTTATCAGTTTTACTTTCTGCTCTCTGGAAACGCCTGCTTCTTTTTTACCTGA
GAGCATTTTTTCGCATTCTGATTTCGTTAGTTTAGATTTTGAATATCTTGTCCAGTTAGTAGGAGTGCCACCTTCCTTTT
CAATAGTGGCGGTAATTTT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|