Detailed information of TA system TA234109

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): IasE-IsrA/-
• Location: 3502293..3502685
• Replicon: chromosome
• Accession: NZ_CP091626
• Organism: Salmonella enterica strain 1165

Toxin (Protein)

• Gene name: IasE
• Uniprot ID: -
• Locus tag: L5507_RS16880
• Protein ID: WP_241467015.1
• Coordinates: 3502440..3502685 (+)
• Length: 82 a.a.

Antitoxin (RNA)

Gene name	IsrA
Locus tag	-
Coordinates	3502293..3502649 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L5507_RS16850	3497545..3498042	-	498	WP_165963407.1	pilus assembly protein	-
L5507_RS16855	3498804..3499508	-	705	Protein_3298	integrase core domain-containing protein	-
L5507_RS16860	3499561..3499875	+	315	WP_133322996.1	SymE family type I addiction module toxin	-
L5507_RS16865	3499942..3500220	-	279	WP_133323248.1	hypothetical protein	-
L5507_RS16870	3500538..3501005	-	468	WP_000828178.1	sugar tyrosine-protein kinase	-
L5507_RS16875	3501823..3502242	-	420	WP_131040133.1	hypothetical protein	-
-	3502293..3502649	-	357	-	-	Antitoxin
L5507_RS16880	3502440..3502685	+	246	WP_241467015.1	hypothetical protein	Toxin
L5507_RS16885	3502752..3503294	-	543	WP_079984650.1	hypothetical protein	-
L5507_RS16890	3503294..3507400	-	4107	WP_133322998.1	RHS repeat-associated core domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	3489640..3503294	13654

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 82 a.a.
• Molecular weight: 8848.00 Da
• Isoelectric Point: 4.0543

>T234109 WP_241467015.1 NZ_CP091626:3502440-3502685 [Salmonella enterica]
MNASDVSVRHINSETCMTACYSQIPSGDCQEEAGFETGRSVTVKISDGCIVLMADGNEVQKLCEQLYQAEQVVKGMWDVI
V

Nucleotide

• Length: 246 bp

>T234109 NZ_LR027516:375691-375993 [Mycobacterium tuberculosis]
TTGATCGCTCCCGGCGACATCGCGCCGCGCCGCGACAGTGAACACGAGCTCTACGTCGCCGTCTTGTCCAACGCGCTCCA
TCGGGCCGCGGACACCGGACGGGTGATCACCTGCCCATTCATTCCGGGCCGGGTCCCCGAGGATCTCTTGGCGATGGTGG
TGGCGGTCGAGCAACCCAACGGCACGCTGCTGCCGGAACTCGTGCAGTGGCTTCATGTTGCCGCGCTCGGTGCGCCACTC
GGCAACGCGGGCGTGGCCGCCCTACGCGAGGCTGCCTCGGTCGTGACAGCTCTGCTCTGTTAG

Antitoxin

Nucleotide

• Length: 357 bp

>AT234109 NZ_CP091626:c3502649-3502293 [Salmonella enterica]
TTCAGCCTGATAAAGCTGTTCGCACAGCTTCTGCACCTCGTTACCGTCCGCCATTAGCACAATACACCCGTCCGAAATCT
TCACCGTCACGCTGCGCCCGGTCTCAAATCCCGCTTCTTCCTGGCAGTCGCCGCTGGGGATTTGTGAGTAACAGGCGGTC
ATGCAGGTTTCGCTGTTGATGTGGCGGACGCTGACGTCGGAGGCATTCATATTTGCTGACTAAATAAATTCTTAATTCTC
CGCCGGATGCTGGCTGATTGTGGAGCTCAGGGTGAGCGAGTATGGGCGCGACATCCTGGCATCGCGCCTCTCTCTCCCCG
GCCAGTGATGAGCAACCGGCTGCCGGGGCCGTATTTT

Structures

Antitoxin